Maternal immunological adaptation during normal pregnancy

B Abu-Raya, C Michalski, M Sadarangani… - Frontiers in …, 2020 - frontiersin.org
The risk and severity of specific infections are increased during pregnancy due to a
combination of physiological and immunological changes. Characterizing the maternal …

[HTML][HTML] Uterine NK cells and macrophages in pregnancy

MM Faas, P De Vos - Placenta, 2017 - Elsevier
The presence of immune cells in the placental bed is important for both mother and child.
Although various immune cells can be found in the placental bed, such as regulatory T cells …

VEGF may contribute to macrophage recruitment and M2 polarization in the decidua

KC Wheeler, MK Jena, BS Pradhan, N Nayak, S Das… - PloS one, 2018 - journals.plos.org
It is increasingly evident that cytokines and growth factors produced in the decidua play a
pivotal role in the regulation of the local immune microenvironment and the establishment of …

Cellular immune responses in the pathophysiology of preeclampsia

D Miller, K Motomura, J Galaz… - Journal of Leukocyte …, 2022 - academic.oup.com
Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …

A leading role for the immune system in the pathophysiology of preeclampsia

E Laresgoiti-Servitje - Journal of leukocyte biology, 2013 - academic.oup.com
Preeclampsia syndrome is characterized by inadequate placentation, because of deficient
trophoblastic invasion of the uterine spiral arteries, leading to placental hypoxia, secretion of …

Roles of microRNAs in preeclampsia

Y Lv, C Lu, X Ji, Z Miao, W Long… - Journal of cellular …, 2019 - Wiley Online Library
Preeclampsia (PE) is a complex disorder that is characterized by hypertension and
proteinuria after the 20th week of pregnancy, and it causes most neonatal morbidity and …

Extracellular ATP and adenosine: the Yin and Yang in immune responses?

MM Faas, T Sáez, P De Vos - Molecular Aspects of Medicine, 2017 - Elsevier
Abstract Extracellular adenosine 5′-triphosphate (ATP) and adenosine molecules are
intimately involved in immune responses. ATP is mostly a pro-inflammatory molecule and is …

The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding

F Schatz, O Guzeloglu-Kayisli, S Arlier… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND Human pregnancy requires robust hemostasis to prevent hemorrhage
during extravillous trophoblast (EVT) invasion of the decidualized endometrium, modification …

Monocytes and macrophages in pregnancy and pre-eclampsia

MM Faas, F Spaans, P De Vos - Frontiers in immunology, 2014 - frontiersin.org
Preeclampsia is an important complication in pregnancy, characterized by hypertension and
proteinuria in the second half of pregnancy. Generalized activation of the inflammatory …

Reprint of: Monocyte subsets in man and other species

L Ziegler-Heitbrock - Cellular immunology, 2014 - Elsevier
Monocytes are white blood cells that belong to the mononuclear phagocyte system. They
derive from precursors in bone marrow, from there they go into blood, where they have a half …