Cell therapies for neurological disorders are entering the clinic and present unique
challenges and opportunities compared with conventional medicines. They have the …

Several types of stem cell have been discovered from germ cells, the embryo, fetus and
adult. Each of these has promised to revolutionize the future of regenerative medicine …

The identification of lung tumor-initiating cells and associated markers may be useful for
optimization of therapeutic approaches and for predictive and prognostic information in lung …

Glioblastoma, the most malignant type of primary brain tumor, is one of the solid cancers
where cancer stem cells have been isolated, and studies have suggested resistance of …

Stem cells have been widely assumed to be capable of replacing lost or damaged cells in a
number of diseases, including Parkinson's disease (PD), in which neurons of the substantia …

Background Neural stem cells (NSCs) represent an optimal tool for studies and therapy of
neurodegenerative diseases. We recently established a v-myc immortalized human NSC …

Stem cell lines that provide a renewable and scaleable supply of central nervous system cell
types would constitute an invaluable resource for basic and applied neurobiology. Here we …

Endocannabinoids are neuromodulators that act as retrograde synaptic messengers
inhibiting the release of different neurotransmitters in cerebral areas such as hippocampus …

Cannabinoids, the active components of marijuana and their endogenous counterparts, act
on the brain and many other organs through the widely expressed CB1 cannabinoid …

We have generated stable, immortalized cell lines of human NSCs from primary human fetal
telencephalon cultures via a retroviral vector encoding v-myc. HB1. F3, one of the human …