Air pollution is the leading cause of lung cancer after tobacco smoking, contributing to 20%
of all lung cancer deaths. Increased risk associated with living near trafficked roads …

The xenobiotic metabolism in the lung, an organ of first entry of xenobiotics into the
organism, is crucial for inhaled compounds entering this organ intentionally (eg drugs) and …

Human diseases and health concerns caused by environmental pollutants are globally
emerging. Therefore, rapid and efficient evaluation of the effects of environmental pollutants …

Prolonged exposure to environmental respirable toxicants can lead to the development and
worsening of severe respiratory diseases such as asthma, chronic obstructive pulmonary …

The antitussive, antioxidant, and anti-inflammatory effects of a walnut (Juglans regia L.)
septum extract (WSE), rich in bioactive compounds were investigated using the citric acid …

Background People are exposed to ambient particulate matter (PM) from multiple sources
simultaneously in both environmental and occupational settings. However, combinatory …

The aim of the study was to develop an in vitro model that mimics the alveolar-capillary
barrier and that allows assessment of the respiratory sensitizing potential of substances. The …

Epidemiological and toxicological studies have reported that ambient fine particulate matter
(PM 2.5) exposure are linked to adverse effects of cardiopulmonary system. An in vitro …

Background The present study aimed to evaluate the potential differences in the biological
effects of two types of spherical silver particles of 20 and 200 nm (Ag20 and Ag200), and of …

Advanced in vitro models are needed to support next-generation risk assessment (NGRA),
moving from hazard assessment based mainly on animal studies to the application of new …