Mechanisms, applications, and challenges of insect RNA interference

KY Zhu, SR Palli - Annual review of entomology, 2020 - annualreviews.org
The RNA interference (RNAi) triggered by short/small interfering RNA (siRNA) was
discovered in nematodes and found to function in most living organisms. RNAi has been …

Insecticide resistance and management strategies in urban ecosystems

F Zhu, L Lavine, S O'Neal, M Lavine, C Foss, D Walsh - Insects, 2016 - mdpi.com
The increased urbanization of a growing global population makes imperative the
development of sustainable integrated pest management (IPM) strategies for urban pest …

DIPA-CRISPR is a simple and accessible method for insect gene editing

Y Shirai, MD Piulachs, X Belles, T Daimon - Cell Reports Methods, 2022 - cell.com
Current approaches for insect gene editing require microinjection of materials into early
embryos. This severely limits the application of gene editing to a great number of insect …

Beyond Drosophila: RNAi In Vivo and Functional Genomics in Insects

X Bellés - Annual review of entomology, 2010 - annualreviews.org
The increasing availability of insect genomes has revealed a large number of genes with
unknown functions and the resulting problem of how to discover these functions. The RNA …

Insect vitellogenin/lipophorin receptors: molecular structures, role in oogenesis, and regulatory mechanisms

M Tufail, M Takeda - Journal of insect physiology, 2009 - Elsevier
Insect vitellogenin and lipophorin receptors (VgRs/LpRs) belong to the low-density
lipoprotein receptor (LDLR) gene superfamily and play a critical role in oocyte development …

Persistence of double-stranded RNA in insect hemolymph as a potential determiner of RNA interference success: evidence from Manduca sexta and Blattella …

JS Garbutt, X Bellés, EH Richards… - Journal of insect …, 2013 - Elsevier
RNA interference (RNAi) is a specific gene silencing mechanism mediated by double-
stranded RNA (dsRNA), which has been harnessed as a useful reverse genetics tool in …

5mC modification orchestrates choriogenesis and fertilization by preventing prolonged ftz-f1 expression

Z Zhao, L Li, R Zeng, L Lin, D Yuan, Y Wen, N Li… - Nature …, 2023 - nature.com
DNA methylation at the fifth position of cytosine (5-methylcytosine, 5mC) is a crucial
epigenetic modification for regulating gene expression, but little is known about how it …

Molecular characterization and RNA interference analysis of vitellogenin receptor from Nilaparvata lugens (Stål)

K Lu, Y Shu, J Zhou, X Zhang, X Zhang, M Chen… - Journal of insect …, 2015 - Elsevier
Vitellogenin receptors (VgRs), members of the low-density lipoprotein receptor (LDLR)
superfamily, are responsible for taking vitellogenin (Vg) into developing oocytes. Here the …

Conserved repressive function of Krüppel homolog 1 on insect metamorphosis in hemimetabolous and holometabolous species

J Lozano, X Belles - Scientific reports, 2011 - nature.com
Insect metamorphosis is regulated by ecdysteroids, which induce molts and juvenile
hormone (JH), which inhibits metamorphic changes. The molecular action of ecdysteroids …

Ecdysone signalling and ovarian development in insects: from stem cells to ovarian follicle formation

X Belles, MD Piulachs - Biochimica et Biophysica Acta (BBA)-Gene …, 2015 - Elsevier
Although a great deal of information is available concerning the role of ecdysone in insect
oogenesis, research has tended to focus on vitellogenesis and choriogenesis. As such, the …