Connexin43 phosphorylation: structural changes and biological effects

JL Solan, PD Lampe - Biochemical Journal, 2009 - portlandpress.com
Vertebrate gap junctions, composed of proteins from the connexin gene family, play critical
roles in embryonic development, co-ordinated contraction of excitable cells, tissue …

Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection

R Schulz, PM Görge, A Görbe, P Ferdinandy… - Pharmacology & …, 2015 - Elsevier
Connexins are widely distributed proteins in the body that are crucially important for heart
and brain functions. Six connexin subunits form a connexon or hemichannel in the plasma …

2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy

JA Towbin, WJ McKenna, DJ Abrams, MJ Ackerman… - Heart rhythm, 2019 - Elsevier
Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium
not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a …

Identification of Cadherin 2 (CDH2) Mutations in Arrhythmogenic Right Ventricular Cardiomyopathy

BM Mayosi, M Fish, G Shaboodien… - Circulation …, 2017 - Am Heart Assoc
Background—Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically
heterogeneous condition caused by mutations in genes encoding desmosomal proteins in …

Micropatterned, electroactive, and biodegradable poly (glycerol sebacate)-aniline trimer elastomer for cardiac tissue engineering

T Hu, Y Wu, X Zhao, L Wang, L Bi, PX Ma… - Chemical Engineering …, 2019 - Elsevier
Developing electroactive elastic scaffolds with micropatterned surface would be beneficial
for cardiac therapy due to their capability of mimicking the anisotropy, electrical propagation …

Cardiac cell–cell junctions in health and disease: electrical versus mechanical coupling

M Noorman, MAG van der Heyden… - Journal of molecular and …, 2009 - Elsevier
Intercalated discs are the membrane sites where individual cardiomyocytes are connected
to each other. Adherens-, desmosomal-, and gap junctions are situated in the intercalated …

Cell-cell connection to cardiac disease

F Sheikh, RS Ross, J Chen - Trends in cardiovascular medicine, 2009 - Elsevier
Intercalated disks (ICDs) are highly organized cell-cell adhesion structures, which connect
cardiomyocytes to one another. They are composed of three major complexes …

Hematopoietic stem cells do not depend on N-cadherin to regulate their maintenance

MJ Kiel, M Acar, GL Radice, SJ Morrison - Cell stem cell, 2009 - cell.com
According to the" osteoblastic niche" model, hematopoietic stem cells (HSCs) are
maintained by N-cadherin-mediated homophilic adhesion to osteoblasts at the bone marrow …

[HTML][HTML] Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues

L Márquez-Rosado, JL Solan, CA Dunn… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Gap junctions, composed of proteins from the connexin family, allow for intercellular
communication between cells in essentially all tissues. There are 21 connexin genes in the …

Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of β-catenin signaling

J Li, D Swope, N Raess, L Cheng… - … and cellular biology, 2011 - Am Soc Microbiol
Mutations in the plakoglobin (JUP) gene have been identified in arrhythmogenic right
ventricular cardiomyopathy (ARVC) patients. However, the mechanisms underlying …