Abstract tRNA-derived fragments (tRFs) are an emerging category of small non-coding
RNAs that are generated from cleavage of mature tRNAs or tRNA precursors. The advance …

The fragments that derive from transfer RNAs (tRNAs) are an emerging category of
regulatory RNAs. Known as tRFs, these fragments were reported for the first time only a …

MODOMICS is a database of RNA modifications that provides comprehensive information
concerning the chemical structures of modified ribonucleosides, their biosynthetic pathways …

Poor reproducibility within and across studies arising from lack of knowledge regarding the
performance of extracellular RNA (exRNA) isolation methods has hindered progress in the …

MINTbase is a repository that comprises nuclear and mitochondrial tRNA-derived fragments
('tRFs') found in multiple human tissues. The original version of MINTbase comprised tRFs …

Non-coding RNA (ncRNA) molecules have fundamental roles in cells and many are also
stable in body fluids as extracellular RNAs. In this study, we used RNA sequencing (RNA …

Transfer RNA fragments (tRFs) are an established class of constitutive regulatory molecules
that arise from precursor and mature tRNAs. RNA deep sequencing (RNA-seq) has greatly …

The “RNA world” represents a novel frontier for the study of fundamental biological
processes and human diseases and is paving the way for the development of new drugs …

The cellular response to stress is an important determinant of disease pathogenesis.
Uncovering the molecular fingerprints of distinct stress responses may identify novel …

A new class of noncoding RNAs, tsRNAs are not only abundant in humans but also have
high tissue specificity. Recently, an increasing number of studies have explored the …