Oxidative stress and advanced lipoxidation and glycation end products (ALEs and AGEs) in aging and age‐related diseases

NT Moldogazieva, IM Mokhosoev… - Oxidative medicine …, 2019 - Wiley Online Library
Oxidative stress is a consequence of the use of oxygen in aerobic respiration by living
organisms and is denoted as a persistent condition of an imbalance between the generation …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2017–2018

DJ Harvey - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …

Hydroxyl radical induced structural perturbations make insulin highly immunogenic and generate an auto-immune response in type 2 diabetes mellitus

M Talha, AR Mir, S Habib, M Abidi, MS Warsi… - … Acta Part A: Molecular …, 2021 - Elsevier
Reactive oxygen species (ROS) cause oxidative damage to proteins and generate
deleterious by-products which induce a breakdown of immune tolerance and produce …

Proteins in human body fluids contain in vivo antigen analog of the melibiose-derived glycation product: MAGE

K Gostomska-Pampuch, A Gamian… - Scientific Reports, 2022 - nature.com
Melibiose-derived AGE (MAGE) is an advanced glycation end-product formed in vitro in
anhydrous conditions on proteins and protein-free amino acids during glycation with …

Glycation, oxidation and glycoxidation of IgG: a biophysical, biochemical, immunological and hematological study

S Islam, Moinuddin, AR Mir, A Raghav… - Journal of …, 2018 - Taylor & Francis
Glycation and oxidation induce structural alterations in the proteins in an interdependent
manner with consequent pathological implications. The published literature presents wide …

Detailed Characterization of Antipathogenic Properties of Human Milk N-Glycome, against Staphylococcus aureus, Indicating Its Targeting on Cell Surface Proteins

B Yin, X Lin, T Wang, L Liu - ACS Infectious Diseases, 2022 - ACS Publications
Human milk N-glycome was previously identified to have strong antipathogenic activities.
This study is aimed to characterize the detailed antibacterial properties and the potential …

Unsaturated aldehyde, 4-hydroxynonenal (HNE) alters the structural integrity of HSA with consequences in the immuno-pathology of rheumatoid arthritis

F Khan, AR Mir, S Islam, M Abidi, MA Husain… - International journal of …, 2018 - Elsevier
Human serum albumin (HSA)-the most abundant plasma protein plays an important role in
the transport of endogenous and exogenous molecules in the body. Its modifications have …

Studies on glycoxidatively modified human IgG: Implications in immuno-pathology of type 2 diabetes mellitus

S Islam, AR Mir, MY Arfat, K Alam, A Ali - International journal of …, 2017 - Elsevier
Structural rearrangements and condensations of proteins under hyperglycemic stress have
been implicated in various pathological disorders. This study aims to probe the role of …

[HTML][HTML] Might hyperbaric oxygen therapy (HBOT) reduce renal injury in diabetic people with diabetes mellitus? From preclinical models to human metabolomics

LE Harrison, C Giardina, LE Hightower… - Cell Stress and …, 2018 - Elsevier
Diabetic kidney disease (DKD) is the leading cause of end-stage renal failure in the western
world. Current treatment of diabetic kidney disease relies on nutritional management and …

Effect of testosterone supplementation on nitroso‐redox imbalance, cardiac metabolism markers, and S100 proteins expression in the heart of castrated male rats

N Regouat, A Cheboub, M Benahmed, A Belarbi… - …, 2018 - Wiley Online Library
The aim of this study was to investigate the effects of castration and testosterone
supplementation on nitroso‐redox status, cardiac metabolism markers, and S100 proteins …