Orchestration of synaptic functions by WAVE regulatory complex-mediated actin reorganization
The WAVE regulatory complex (WRC), composed of five components—Cyfip1/Sra1,
WAVE/Scar, Abi, Nap1/Nckap1, and Brk1/HSPC300—is essential for proper actin …
WAVE/Scar, Abi, Nap1/Nckap1, and Brk1/HSPC300—is essential for proper actin …
The WAVE complex in developmental and adulthood brain disorders
HG Kim, C Berdasco, AC Nairn, Y Kim - Experimental & Molecular …, 2025 - nature.com
Actin polymerization and depolymerization are fundamental cellular processes required not
only for the embryonic and postnatal development of the brain but also for the maintenance …
only for the embryonic and postnatal development of the brain but also for the maintenance …
Expression of INPP5D Isoforms in Human Brain: Impact of Alzheimer's Disease Neuropathology and Genetics
The single nucleotide polymorphisms rs35349669 and rs10933431 within Inositol
Polyphosphate-5-Phosphatase D (INPP5D) are strongly associated with Alzheimer's …
Polyphosphate-5-Phosphatase D (INPP5D) are strongly associated with Alzheimer's …
The effect of Abi3 locus deletion on the progression of Alzheimer's disease-related pathologies
Human genetics studies of Alzheimer's disease (AD) have identified the ABI3 gene as a
candidate risk gene for AD. Because ABI3 is highly expressed in microglia, the brain's …
candidate risk gene for AD. Because ABI3 is highly expressed in microglia, the brain's …
[PDF][PDF] Dissecting the role of the ABI3 S209F variant in human microglia–A functional
MS Pasculli - Neuroscience, 2024 - helda.helsinki.fi
The S209F variant of the Abelson Interactor family member 3 (ABI3) gene has emerged as a
risk factor for late-onset Alzheimer's Disease (LOAD). The ABI3 protein is functionally related …
risk factor for late-onset Alzheimer's Disease (LOAD). The ABI3 protein is functionally related …
The Role of ABI3 in Obesity and Metabolic Regulation
DC Smith - 2024 - scholarworks.iupui.edu
Abstract Abelson Interactor Protein 3 is an adaptor protein involved in cytoskeletal
remodeling. ABI3 is predominantly expressed within mononuclear phagocytotic immune …
remodeling. ABI3 is predominantly expressed within mononuclear phagocytotic immune …