Circulating nucleic acids in plasma and serum (CNAPS): applications in oncology

JA González-Masiá, D García-Olmo… - OncoTargets and …, 2013 - Taylor & Francis
The presence of small amounts of circulating nucleic acids in plasma and serum (CNAPS) is
not a new finding. The verification that such amounts are significantly increased in cancer …

Liquid Biopsy of Hepatocellular Carcinoma: Circulating Tumor‐Derived Biomarkers

CQ Yin, CH Yuan, Z Qu, Q Guan, H Chen… - Disease …, 2016 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the second leading cause of cancer‐related death
worldwide due to latent liver disease, late diagnosis, and nonresponse to systemic …

Hypermethylation of CCND2 in lung and breast cancer is a potential biomarker and drug target

CS Hung, SC Wang, YT Yen, TH Lee, WC Wen… - International journal of …, 2018 - mdpi.com
Lung and breast cancer are the leading causes of mortality in women worldwide. The
discovery of molecular alterations that underlie these two cancers and corresponding drugs …

[HTML][HTML] Aberrant DNA methylation of G-protein-coupled bile acid receptor Gpbar1 (TGR5) is a potential biomarker for hepatitis B Virus associated hepatocellular …

LY Han, YC Fan, NN Mu, S Gao, F Li, XF Ji… - … Journal of Medical …, 2014 - ncbi.nlm.nih.gov
Background: G-protein-coupled bile acid receptor Gpbar1 (TGR5) is a newly identified liver
tumor suppressor in carcinogenesis. This present study was therefore to determine the …

Sex and race-related DNA methylation changes in hepatocellular carcinoma

W Ye, S Siwko, RYL Tsai - International journal of molecular sciences, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is the sixth most common cancer and fourth leading cause
of cancer-related death worldwide. The number of HCC cases continues to rise despite …

DNA methylation: potential biomarker in Hepatocellular Carcinoma

WC Mah, CGL Lee - Biomarker research, 2014 - Springer
Hepatocellular Carcinoma (HCC) is one of the most common cancers in the world and it is
often associated with poor prognosis. Liver transplantation and resection are two currently …

Clinical significance and biological roles of cyclins in gastric cancer

HP Zhang, SY Li, JP Wang, J Lin - OncoTargets and therapy, 2018 - Taylor & Francis
Background and aim Cyclins have been reported to be overexpressed with poor prognosis
in several human cancers. However, limited numbers of studies evaluated the expressions …

Is cell-free DNA testing in hepatocellular carcinoma ready for prime time?

S Jeepalyam, A Sheel, A Ejaz, E Miller… - International journal of …, 2023 - mdpi.com
Revamping the current biomarker landscape of hepatocellular carcinoma (HCC) with cell-
free DNA (cfDNA) could improve overall outcomes. The use of commercially available …

Quantitative methylation analysis reveals gender and age differences in p16 INK 4a hypermethylation in hepatitis B virus‐related hepatocellular carcinoma

Y Wang, J Cheng, C Xu, S Liu, S Jiang, Q Xu… - Liver …, 2012 - Wiley Online Library
Background Frequent promoter hypermethylation of the inhibitors in either Rb or p53
pathways is associated with the hepatocellular carcinoma (HCC) development. Objective To …

The other side of the coin: The tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND–CDK4 …

X Lou, J Zhang, S Liu, X Lou, DJ Liao - Cell Cycle, 2014 - Taylor & Francis
Although cancer-regulatory genes are dichotomized to oncogenes and tumor-suppressor
gene s, in reality they can be oncogenic in one situation but tumor-suppressive in another …