Metabolic fingerprinting as a diagnostic tool

DI Ellis, WB Dunn, JL Griffin, JW Allwood… - …, 2007 - Taylor & Francis
Within the framework of systems biology, functional analyses at all 'omic levels have seen an
intense level of activity during the first decade of the twenty-first century. These include …

Vibrational spectroscopy: a clinical tool for cancer diagnostics

C Kendall, M Isabelle, F Bazant-Hegemark… - Analyst, 2009 - pubs.rsc.org
Vibrational spectroscopy techniques have demonstrated potential to provide non-
destructive, rapid, clinically relevant diagnostic information. Early detection is the most …

Measurement of elastic properties of prostate cancer cells using AFM

EC Faria, N Ma, E Gazi, P Gardner, M Brown… - Analyst, 2008 - pubs.rsc.org
This communication reports that three prostate cancer cells of differing metastatic potential
were discriminated based on their Young's moduli (LNCaP–287±52 N m− 2, PC-3 …

Towards a practical Fourier transform infrared chemical imaging protocol for cancer histopathology

R Bhargava - Analytical and bioanalytical chemistry, 2007 - Springer
Fourier transform infrared (FTIR) chemical imaging is a strongly emerging technology that is
being increasingly applied to examine tissues in a high-throughput manner. The resulting …

System for identifying and sorting living cells

M Wagner, J Heanue - US Patent 8,941,062, 2015 - Google Patents
In embodiments of the present invention, a system and method of cytometry may include
presenting a single sperm cell to at least one laser source configured to deliver light to the …

RMieS‐EMSC correction for infrared spectra of biological cells: Extension using full Mie theory and GPU computing

P Bassan, A Kohler, H Martens, J Lee… - Journal of …, 2010 - Wiley Online Library
In the field of biomedical infrared spectroscopy it is often desirable to obtain spectra at the
cellular level. Samples consisting of isolated single biological cells are particularly unsuited …

LDA vs. QDA for FT-MIR prostate cancer tissue classification

LFS Siqueira, RFA Júnior, AA de Araújo… - Chemometrics and …, 2017 - Elsevier
Discrimination/classification of biological material a ta molecular level is one of the key aims
of chemometrics applied to biospectroscopic data. Two discriminant functions, namely …

Raman tweezers and their application to the study of singly trapped eukaryotic cells

RD Snook, TJ Harvey, E Correia Faria… - Integrative …, 2009 - academic.oup.com
In this review the recent emergence of Raman tweezers as an analytical technique for single
eukaryotic cell analysis is described. The Raman tweezer technique combines Raman …

Spectral discrimination of live prostate and bladder cancer cell lines using Raman optical tweezers

TJ Harvey, EC Faria, A Henderson… - Journal of …, 2008 - spiedigitallibrary.org
An investigation into the use of Raman optical tweezers to study urological cell lines is
reported, with the ultimate aim of determining the presence of malignant CaP cells in urine …

Single-cell analysis using Fourier transform infrared microspectroscopy

J Doherty, G Cinque, P Gardner - Applied Spectroscopy Reviews, 2017 - Taylor & Francis
Fourier transform infrared spectroscopy (FTIR) is a well-established, non-destructive method
of obtaining chemical information from biological samples such as tissues and cells. This …