Tau-targeting therapies for Alzheimer disease: current status and future directions
Alzheimer disease (AD) is the most common cause of dementia in older individuals. AD is
characterized pathologically by amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the …
characterized pathologically by amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the …
[HTML][HTML] Microglial activation states and their implications for Alzheimer's Disease
Z Valiukas, K Tangalakis, V Apostolopoulos… - The Journal of …, 2025 - Elsevier
Alzheimer's Disease (AD) is a chronic neurodegenerative disorder characterized by the
accumulation of toxic amyloid-beta (Aβ) plaques and neurofibrillary tangles (NFTs) of tau …
accumulation of toxic amyloid-beta (Aβ) plaques and neurofibrillary tangles (NFTs) of tau …
The rate of decrease in brain perfusion in progressive supranuclear palsy and corticobasal syndrome may be impacted by glycemic variability—A pilot study
P Alster, A Dunalska, B Migda, N Madetko… - Frontiers in …, 2021 - frontiersin.org
Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are tauopathic
parkinsonian syndromes, presently lacking disease-modifying treatments. Patients affected …
parkinsonian syndromes, presently lacking disease-modifying treatments. Patients affected …
Tau PET burden in Brodmann areas 35 and 36 is associated with individual differences in cognition in non-demented older adults
Introduction The accumulation of neurofibrillary tau tangles, a neuropathological hallmark of
Alzheimer's disease (AD), occurs in medial temporal lobe (MTL) regions early in the disease …
Alzheimer's disease (AD), occurs in medial temporal lobe (MTL) regions early in the disease …
Brain functional specialization and cooperation in Alzheimer's disease
Y Wu, M Gao, L Lv, Y Yan, L Gao, Z Geng… - Brain and …, 2024 - Wiley Online Library
Background Cerebral specialization and interhemispheric cooperation are two vital features
of the human brain. Their dysfunction may be associated with disease progression in …
of the human brain. Their dysfunction may be associated with disease progression in …
Morphometry of medial temporal lobe subregions using high‐resolution T2‐weighted MRI in ADNI3: Why, how, and what's next?
PA Yushkevich, R Ittyerah, Y Li… - Alzheimer's & …, 2024 - Wiley Online Library
This paper for the 20th anniversary of the Alzheimer's Disease Neuroimaging Initiative
(ADNI) provides an overview of magnetic resonance imaging (MRI) of medial temporal lobe …
(ADNI) provides an overview of magnetic resonance imaging (MRI) of medial temporal lobe …
Body mass index related to executive function and hippocampal subregion volume in subjective cognitive decline
R Chen, G Cai, S Xu, Q Sun, J Luo, Y Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Objective This study aims to explore whether body mass index (BMI) level affects the
executive function and hippocampal subregion volume of subjective cognitive decline …
executive function and hippocampal subregion volume of subjective cognitive decline …
The pons as an optimal background reference region for spinal 18F-FET PET/MRI evaluation
J Huang, J Wang, B Cui, H Yang, D Tian, J Ma… - EJNMMI research, 2024 - Springer
Background This study aims to evaluate the effect of various background reference regions
on spinal 18F-FET PET imaging, with a focus on distinguishing between spinal tumors and …
on spinal 18F-FET PET imaging, with a focus on distinguishing between spinal tumors and …
[PDF][PDF] The Journal of Prevention of Alzheimer's Disease
abstract Alzheimer's Disease (AD) is a chronic neurodegenerative disorder characterized by
the accumulation of toxic amyloid-beta (A𝛽) plaques and neurofibrillary tangles (NFTs) of …
the accumulation of toxic amyloid-beta (A𝛽) plaques and neurofibrillary tangles (NFTs) of …