Drug development, Brazilian biodiversity and political choices: Where are we heading?

PMP Ferreira, DDR Arcanjo… - Journal of Toxicology and …, 2023 - Taylor & Francis
The aim of this review was to (i) acknowledge structural advantages of natural products
(NPs) for designing therapeutic drugs;(ii) emphasize how wildlife conservation is socially …

Marine natural product peptides with therapeutic potential: Chemistry, biosynthesis, and pharmacology

V Gogineni, MT Hamann - Biochimica et Biophysica Acta (BBA)-General …, 2018 - Elsevier
The oceans are a uniquely rich source of bioactive metabolites, of which sponges have
been shown to be among the most prolific producers of diverse bioactive secondary …

Marine sponge natural products with anticancer potential: An updated review

C Calcabrini, E Catanzaro, A Bishayee, E Turrini… - Marine drugs, 2017 - mdpi.com
Despite the huge investment into research and the significant effort and advances made in
the search for new anticancer drugs in recent decades, cancer cure and treatment continue …

Au/Polypyrrole@Fe3O4 Nanocomposites for MR/CT Dual-Modal Imaging Guided-Photothermal Therapy: An in Vitro Study

W Feng, X Zhou, W Nie, L Chen, K Qiu… - … Applied Materials & …, 2015 - ACS Publications
Construction of multifunctional nanocomposites as theranostic platforms has received
considerable biomedical attention. In this study, a triple-functional theranostic agent based …

Bioactive peptide of marine origin for the prevention and treatment of non-communicable diseases

R Pangestuti, SK Kim - Marine Drugs, 2017 - mdpi.com
Non-communicable diseases (NCD) are the leading cause of death and disability
worldwide. The four main leading causes of NCD are cardiovascular diseases, cancers …

Cyclodepsipeptides from marine sponges: Natural agents for drug research

GSB Andavan, R Lemmens-Gruber - Marine drugs, 2010 - mdpi.com
A number of natural products from marine sponges, such as cyclodepsipeptides, have been
identified. The structural characteristics of this family of cyclic peptides include various …

Natural cyclopeptides as anticancer agents in the last 20 years

JN Zhang, YX Xia, HJ Zhang - International Journal of Molecular Sciences, 2021 - mdpi.com
Cyclopeptides or cyclic peptides are polypeptides formed by ring closing of terminal amino
acids. A large number of natural cyclopeptides have been reported to be highly effective …

[HTML][HTML] Marine peptides in breast cancer: Therapeutic and mechanistic understanding

S Ahmed, H Mirzaei, M Aschner, A Khan… - Biomedicine & …, 2021 - Elsevier
Breast cancer is the most prevalent invasive form of cancer in females and posing a great
challenge for overcoming disease burden. The growth in global cancer deaths mandates the …

Marine pharmacology in 2005–2006: Antitumour and cytotoxic compounds

AMS Mayer, KR Gustafson - European Journal of Cancer, 2008 - Elsevier
During 2005 and 2006, marine pharmacology research directed towards the discovery and
development of novel antitumour agents was reported in 171 peer-reviewed articles. The …

In vitro and in vivo toxicity studies of copper sulfide nanoplates for potential photothermal applications

W Feng, W Nie, Y Cheng, X Zhou, L Chen, K Qiu… - … , Biology and Medicine, 2015 - Elsevier
Copper sulfide (CuS) has emerged as a promising photothermal agent. However, its
potential toxic effects still remained poorly understood. Herein, CuS nanoplates were …