Abstract The Ca2+-sensing receptor (CaSR) is a dimeric family CG protein-coupled receptor
that is expressed in calcitropic tissues such as the parathyroid glands and the kidneys and …

Intestine is always exposed to external environment and intestinal microorganism; thus it is
more sensitive to dysfunction and dysbiosis, leading to intestinal inflammation, such as …

The calcium-sensing receptor (CaSR) is a class CG protein–coupled receptor that responds
to multiple endogenous agonists and allosteric modulators, including divalent and trivalent …

Diet is a major factor determining gut microbiota composition and perturbances in this
complex ecosystem are associated with the inflammatory bowel disease (IBD). Here, we …

The gut microbiome is a collection of microorganisms and parasites in the gastrointestinal
tract. Many factors can affect this community's composition, such as age, sex, diet …

A complete carcinogen, ultraviolet B (UVB) radiation (290–320 nm), is the major cause of
skin cancer. UVB-induced systemic immunosuppression that contributes to …

Long‐term exposure to high glucose induces vascular endothelial inflammation that can
result in cardiovascular disease. Astragaloside IV (As‐IV) is widely used for anti …

Background Impaired intestinal barrier integrity plays a crucial role in the development of
many diseases such as obesity, inflammatory bowel disease, and type 2 diabetes. Thus …

Nutrient sensing plays an important role in ensuring that appropriate digestive or hormonal
responses are elicited following the ingestion of fuel substrates. Mechanisms of nutrient …

The haemoglobin content in meat is consistently associated with an increased risk of
colorectal cancer, whereas calcium may play a role as a chemopreventive agent. Using …