Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections

JMV Makabenta, A Nabawy, CH Li… - Nature Reviews …, 2021 - nature.com
Antibiotic-resistant bacterial infections arising from acquired resistance and/or through
biofilm formation necessitate the development of innovative 'outside of the box'therapeutics …

Nanotechnology as a promising approach to combat multidrug resistant bacteria: a comprehensive review and future perspectives

HF Hetta, YN Ramadan, AI Al-Harbi, E A. Ahmed… - Biomedicines, 2023 - mdpi.com
The wide spread of antibiotic resistance has been alarming in recent years and poses a
serious global hazard to public health as it leads to millions of deaths all over the world. The …

Multifaceted application of silica nanoparticles. A review

PG Jeelani, P Mulay, R Venkat, C Ramalingam - Silicon, 2020 - Springer
Nanoparticles have immense industrial, biotechnological, and biomedical/pharmaceutical
applications due to their pliability in structure, size, biocompatibility, high surface area, and …

Perspectives on usage of functional nanomaterials in antimicrobial therapy for antibiotic-resistant bacterial infections

A Karnwal, G Kumar, G Pant, K Hossain, A Ahmad… - ACS …, 2023 - ACS Publications
The clinical applications of nanotechnology are emerging as widely popular, particularly as
a potential treatment approach for infectious diseases. Diseases associated with multiple …

Current applications of nanoparticles in infectious diseases

H Zazo, CI Colino, JM Lanao - Journal of Controlled Release, 2016 - Elsevier
For decades infections have been treated easily with drugs. However, in the 21st century,
they may become lethal again owing to the development of antimicrobial resistance …

Antibiotic resistance in Pseudomonas aeruginosa and alternative therapeutic options

M Chatterjee, CP Anju, L Biswas, VA Kumar… - International Journal of …, 2016 - Elsevier
Pseudomonas aeruginosa is a leading cause of nosocomial infections and is responsible
for∼ 10% of all hospital-acquired infections worldwide. It continues to pose a therapeutic …

Nanotechnology-based drug delivery systems for control of microbial biofilms: a review

MA Dos Santos Ramos, PB Da Silva… - International journal …, 2018 - Taylor & Francis
Since the dawn of civilization, it has been understood that pathogenic microorganisms
cause infectious conditions in humans, which at times, may prove fatal. Among the different …

Lipid and polymer nanoparticles for drug delivery to bacterial biofilms

K Forier, K Raemdonck, SC De Smedt… - Journal of controlled …, 2014 - Elsevier
Biofilms are matrix-enclosed communities of bacteria that show increased antibiotic
resistance and the capability to evade the immune system. They can cause recalcitrant …

Controlled release and targeted drug delivery with poly (lactic-co-glycolic acid) nanoparticles: reviewing two decades of research

A Zeb, M Gul, TTL Nguyen, HJ Maeng - Journal of Pharmaceutical …, 2022 - Springer
Background Controlled release and targeted delivery of the drug payload are the two most
fascinating applications of nanoparticle-based systems explored in the recent past. The …

Nanocarriers for antibiotics: a promising solution to treat intracellular bacterial infections

N Abed, P Couvreur - International journal of antimicrobial agents, 2014 - Elsevier
In the field of antibiotherapy, intracellular infections remain difficult to eradicate mainly due to
the poor intracellular penetration of most of the commonly used antibiotics. Bacteria have …