The emphasis in contemporary medical oncology has been “precision” or “personalized”
medicine, terms that imply a strategy to improve efficacy through targeted therapies. Similar …

Epidemiology Vulvar cancer can be classified into two groups according to predisposing
factors: the first type correlates with a HPV infection and occurs mostly in younger patients …

PURPOSE The Groningen International Study on Sentinel nodes in Vulvar cancer
(GROINSS-V)-II investigated whether inguinofemoral radiotherapy is a safe alternative to …

Background Retrospective single-centre series have shown the feasibility of sentinel lymph-
node (SLN) identification in endometrial cancer. We did a prospective, multicentre cohort …

Abstract Objective In 2008 GROINSS-VI, the largest validation trial on the sentinel node (SN)
procedure in vulvar cancer, showed that application of the SN-procedure in patients with …

There will be an estimated 6190 new cases of vulvar cancer in 2018, accounting for 0.4% of
all cancers. This is primarily a disease of the elderly with a median age at diagnosis of 68 …

Vulvar cancer is a rare gynecologic malignancy. Ninety percent of vulvar cancers are
predominantly squamous cell carcinomas (SCCs), which can arise through human …

Background: Women with node-positive vulvar cancer have a high risk for disease
recurrence. Indication criteria for adjuvant radiotherapy are controversial. This study was …

Objective There is great need for better risk stratification in vulvar squamous cell carcinoma
(VSCC). Our aim was to define the prognostic significance of stratifying VSCC based on p16 …

Lower extremity lymphedema is a chronic, often irreversible condition that affects many
patients treated for gynecologic malignancies, with published rates as high as 70% in select …