Glioblastoma (GBM) is one of the most aggressive and lethal human brain tumors. At
present, GBMs are divided in primary and secondary on the basis of the mutational status of …

Malignant gliomas, the most common type of primary brain tumor in adults, are associated
with disproportionate cancer-related morbidity and mortality. Recently, there have been …

Malignant gliomas such as glioblastoma multiforme (GBM) present some of the greatest
challenges in the management of cancer patients worldwide, despite notable recent …

The value of perfusion and diffusion-weighted MRI in differentiating histological subtypes
according to the 2007 WHO glioma classification scheme (ie astrocytoma vs …

Malignant gliomas are one of the deadliest forms of brain cancer and despite advancements
in treatment, patient prognosis remains poor, with an average survival of 15 months …

Malignant brain tumors are among the most lethal cancers, and conventional therapies are
largely limited to palliation. Novel therapies targeted against specific molecular pathways …

Glioblastoma is the commonest primary brain tumor, as well as the deadliest. Malignant
gliomas such as glioblastoma multiforme (GBM) present some of the greatest challenges in …

Chimeric antigen receptor T cell (CAR-T) therapy has been shown to be an effective strategy
for combatting non-solid tumors; however, CAR-T therapy is still a challenge for solid tumors …

The poor prognosis of Glioblastoma Multiforme (GBM) is due to a high resistance to
conventional treatments and to the presence of a subpopulation of glioma stem cells …

Improved delivery materials are needed to enable siRNA transport across biological
barriers, including the blood–brain barrier (BBB), to treat diseases like brain cancer. We …