Acute-on-chronic liver failure (ACLF) is a multifaceted condition with poor treatment options
and high short-term mortality. ACLF can develop in patients with or without liver cirrhosis …

Introduction Chronic liver disease is due to various causes of persistent liver damage and
will eventually lead to the development of liver fibrosis. If no treatment is initiated, this …

With prevalence high and rising given the close relationship with obesity and diabetes
mellitus, non-alcoholic fatty liver disease (NAFLD) is progressively becoming the most …

Cirrhosis is end-stage liver disease resulting from various etiologies and is a common cause
of death worldwide. The progression from compensated to decompensated cirrhosis to …

Cirrhosis is the fifth leading cause of death in adults. Advanced cirrhosis can cause
significant portal hypertension (PH), which is responsible for many of the complications …

Issues Alcohol use has been shown to impact on various forms of liver disease, not
restricted to alcoholic liver disease. Approach We developed a conceptual framework based …

Background & Aims HNF4α, a master regulator of liver development and the mature
hepatocyte phenotype, is down-regulated in chronic and inflammatory liver disease. We …

Background Extracellular volume (ECV) correlates with the degree of liver fibrosis. Purpose
To analyze the performance of liver MRI‐based ECV evaluations with different blood pool …

MIF/CD74 signaling pathway and autophagy may be closely related to liver fibrosis. Vanillic
acid (VA) is likely to have an anti-liver fibrosis effect, although related studies have not been …

Various types of liver disease exist, such as hepatitis and alcoholic liver disease. These liver
diseases can result in scarring of liver tissue, cirrhosis, and finally liver failure. During liver …