Progress and Challenges in the Field of Snakebite Envenoming Therapeutics

JM Gutiérrez, N R. Casewell… - Annual Review of …, 2024 - annualreviews.org
Snakebite envenoming kills and maims hundreds of thousands of people every year,
especially in the rural settings of tropical regions. Envenomings are still treated with animal …

Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins

IS Khalek, RR Senji Laxme, YTK Nguyen… - Science Translational …, 2024 - science.org
Snakebite envenoming is a major global public health concern for which improved therapies
are urgently needed. The antigenic diversity present in snake venom toxins from various …

[HTML][HTML] Towards better antivenoms: navigating the road to new types of snakebite envenoming therapies

S Thumtecho, NJ Burlet, A Ljungars… - Journal of Venomous …, 2023 - SciELO Brasil
Snakebite envenoming is a significant global health challenge, and for over a century,
traditional plasma-derived antivenoms from hyperimmunized animals have been the primary …

Metabolomics and proteomics: synergistic tools for understanding snake venom inhibition

SS Hussain, JD Kingsley - Archives of Toxicology, 2025 - Springer
Snake envenomation presents a significant global health challenge, especially in rural
areas of tropical and subtropical regions. Traditional antivenom therapies face limitations …

[HTML][HTML] Improving in vivo assays in snake venom and antivenom research: A community discussion

AE Marriott, NR Casewell, E Lilley, JM Gutiérrez… - …, 2024 - ncbi.nlm.nih.gov
On the 26 th January 2023, a free to attend,'improving in vivo snake venom research: a
community discussion'meeting was held virtually. This webinar brought together researchers …

[HTML][HTML] Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of mamba (Elapidae: Dendroaspis spp.) snakes

A Gómez, A Sánchez, G Durán, M Villalta, Á Segura… - Toxicon: X, 2024 - Elsevier
Snakebite envenomation is a neglected tropical disease posing a high toll of mortality and
morbidity in sub-Saharan Africa. Polyspecific antivenoms of broad effectiveness and …

ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming

SK Menzies, R Arinto-Garcia, FG Amorim, IA Cardoso… - Toxins, 2023 - mdpi.com
Snakebite envenoming can be a life-threatening medical emergency that requires prompt
medical intervention to neutralise the effects of venom toxins. Each year up to 138,000 …

Design of consensus toxins and their use for the discovery of broadly neutralizing antibodies

AD Jensen - 2023 - orbit.dtu.dk
Snakebite envenoming remains a significant global health challenge, impacting millions of
people annually, particularly in regions with limited access to medical care. The primary …