Efficacy and underlying mechanisms of berberine against lipid metabolic diseases: a review

Y Cai, Q Yang, Y Yu, F Yang, R Bai… - Frontiers in pharmacology, 2023 - frontiersin.org
Lipid-lowering therapy is an important tool for the treatment of lipid metabolic diseases,
which are increasing in prevalence. However, the failure of conventional lipid-lowering …

Role of serum amyloid A in atherosclerosis

P Shridas, LR Tannock - Current opinion in lipidology, 2019 - journals.lww.com
Role of serum amyloid A in atherosclerosis : Current Opinion in Lipidology Role of serum amyloid
A in atherosclerosis : Current Opinion in Lipidology Log in or Register Subscribe to …

High-density lipoproteins decrease proinflammatory activity and modulate the innate immune response

NA Taborda, Y Blanquiceth… - Journal of Interferon & …, 2019 - liebertpub.com
Atherosclerosis, a chronic inflammatory disease of the arterial wall, is the leading cause of
cardiac disorders and stroke. The onset and progression of these diseases are linked with …

Hepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice

S Hu, Y Zhu, X Zhao, R Li, G Shao, D Gong, C Hu… - Developmental Cell, 2023 - cell.com
High-density lipoprotein (HDL) metabolism is regulated by complex interplay between the
scavenger receptor group B type 1 (SR-BI) and multiple signaling molecules in the liver …

Searching for Atherosclerosis Biomarkers by Proteomics: A Focus on Lesion Pathogenesis and Vulnerability

G Nieddu, M Formato, AJ Lepedda - International Journal of Molecular …, 2023 - mdpi.com
Plaque rupture and thrombosis are the most important clinical complications in the
pathogenesis of stroke, coronary arteries, and peripheral vascular diseases. The …

Genetic variations in IKZF3, LET7‐a2, and CDKN2B‐AS1: Exploring associations with metabolic syndrome susceptibility and clinical manifestations

A Paniri, MM Hosseini, S Fattahi… - Journal of Clinical …, 2024 - Wiley Online Library
Background and aim Metabolic syndrome (MetS) increases the risk of atherosclerosis and
diabetes, but there are no approved predictive markers. This study assessed the role of …

HDL and scavenger receptor class B Type I (SRBI)

H Yu - HDL Metabolism and Diseases, 2022 - Springer
The scavenger receptor class B type I (SR-BI) is a versatile HDL receptor protein. It is highly
expressed in liver and steroidogenic tissues. SR-BI regulates selective uptake of cholesterol …

HDL as bidirectional lipid vectors: Time for new paradigms

M Luna-Luna, E Niesor, Ó Pérez-Méndez - Biomedicines, 2022 - mdpi.com
The anti-atherogenic properties of high-density lipoproteins (HDL) have been explained
mainly by reverse cholesterol transport (RCT) from peripheral tissues to the liver. The RCT …

[HTML][HTML] The Molecular Bases of Anti-Oxidative and Anti-Inflammatory Properties of Paraoxonase 1

H Jakubowski - Antioxidants, 2024 - mdpi.com
The anti-oxidative and anti-inflammatory properties of high-density lipoprotein (HDL) are
thought to be mediated by paraoxonase 1 (PON1), a calcium-dependent hydrolytic enzyme …

[HTML][HTML] Apolipoprotein M promotes the anti-inflammatory effect of high-density lipoprotein by binding to scavenger receptor BI

S Yao, G Luo, H Liu, J Zhang, Y Zhan… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Inflammation participates pivotally in the pathogenesis of atherosclerosis.
Apolipoprotein M (apoM) is a high-density lipoprotein (HDL)-associated plasma protein that …