Implant infections: adhesion, biofilm formation and immune evasion

CR Arciola, D Campoccia, L Montanaro - Nature reviews microbiology, 2018 - nature.com
Medical device-associated infections account for a large proportion of hospital-acquired
infections. A variety of opportunistic pathogens can cause implant infections, depending on …

Pathogenesis and Clinical Relevance of Candida Biofilms in Vulvovaginal Candidiasis

C Rodríguez-Cerdeira, E Martínez-Herrera… - Frontiers in …, 2020 - frontiersin.org
The ability of Candida spp. to form biofilms is crucial for its pathogenicity, and thus, it should
be considered an important virulence factor in vulvovaginal candidiasis (VVC) and recurrent …

Convergence of Staphylococcus aureus Persister and Biofilm Research: Can Biofilms Be Defined as Communities of Adherent Persister Cells?

EM Waters, SE Rowe, JP O'Gara, BP Conlon - PLoS pathogens, 2016 - journals.plos.org
The remarkable tolerance of bacterial biofilms to antimicrobial drugs underpins their role in
chronic and recurring infections. Staphylococcus aureus biofilms are embedded in an …

Immune response modulation by Pseudomonas aeruginosa persister cells

CJ Hastings, GE Himmler, A Patel, CNH Marques - Mbio, 2023 - Am Soc Microbiol
Bacterial persister cells—a metabolically dormant subpopulation tolerant to antimicrobials—
contribute to chronic infections and are thought to evade host immunity. In this work, we …

Subversion of the complement system by pseudomonas aeruginosa

CJ Hastings, SS Syed, CNH Marques - Journal of Bacteriology, 2023 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic pathogen heavily implicated in chronic
diseases. Immunocompromised patients that become infected with P. aeruginosa usually …

The Agr Quorum Sensing System Represses Persister Formation through Regulation of Phenol Soluble Modulins in Staphylococcus aureus

T Xu, XY Wang, P Cui, YM Zhang, WH Zhang… - Frontiers in …, 2017 - frontiersin.org
The opportunistic pathogen Staphylococcus aureus has become an increasing threat to
public health. While the Agr quorum sensing (QS) system is a master regulator of S. aureus …

Antibiotic tolerance and the alternative lifestyles of Staphylococcus aureus

LMG Bui, BP Conlon, SP Kidd - Essays in biochemistry, 2017 - portlandpress.com
Staphylococcus aureus has an incredible ability to survive, either by adapting to
environmental conditions or defending against exogenous stress. Although there are …

A quantitative survey of bacterial persistence in the presence of antibiotics: towards antipersister antimicrobial discovery

JE Salcedo-Sora, DB Kell - Antibiotics, 2020 - mdpi.com
Background: Bacterial persistence to antibiotics relates to the phenotypic ability to survive
lethal concentrations of otherwise bactericidal antibiotics. The quantitative nature of the time …

Identification of essential oils with activity against stationary phase Staphylococcus aureus

S Xiao, P Cui, W Shi, Y Zhang - BMC complementary medicine and …, 2020 - Springer
Background Staphylococcus aureus is the most dominant human pathogen, responsible for
a variety of chronic and severe infections. There is mounting evidence that persisters are …

Novel Therapies for Biofilm-Based Candida spp. Infections

L Černáková, C Light, B Salehi… - … Infectious Diseases and …, 2019 - Springer
The presence of fungal infections continue to grow worldwide, mostly in immunosuppressed
patients, and in individuals with continued antimicrobial treatments. Candida spp. are the …