The pulmonary endothelium is a metabolically active continuous monolayer of squamous
endothelial cells that internally lines blood vessels and mediates key processes involved in …

Lung ischemia-reperfusion injury (LIRI) and primary graft dysfunction are leading causes of
morbidity and mortality among lung transplant recipients. Although extensive research …

A damaged endothelium is an underlying condition of the many complications of COVID-19
patients. The increased mortality risk associated with diseases that have underlying …

Background Potential routes whereby systemic inflammation, oxidative stress and
mitochondrial dysfunction may drive the development of endothelial dysfunction and …

Vascular age is determined by functional and structural changes in the arterial wall. When
measured by its proxy, pulse wave velocity, it has been shown to predict cardiovascular and …

Sepsis, a prevalent critical condition in clinics, continues to be the leading cause of death
from infections and a global healthcare issue. Among the organs susceptible to the harmful …

Primary graft dysfunction (PGD) is one of the most common complications in the early
postoperative period and is the most common cause of death in the first postoperative …

Importance Inhaled nitric oxide (iNO) is commonly administered for selectively inhaled
pulmonary vasodilation and prevention of oxidative injury after lung transplant (LT). Inhaled …

Alzheimer's disease (AD) is characterized by the progressive disturbance in cognition and
affects approximately 36 million people, worldwide. However, the drugs used to treat this …

Objectives. Coronary reperfusion procedure leads to ischemia/reperfusion injury of the heart
(IRI). IRI arises from increased degradation of myosin light chains and increased activity of …