Beyond the lipid-bilayer: interaction of polymers and nanoparticles with membranes

M Schulz, A Olubummo, WH Binder - Soft Matter, 2012 - pubs.rsc.org
Membranes can be fabricated either from lipid or polymer molecules, leading to the
formation of liposomes or polymersomes. In all types of liposomal membranes, the issue of …

Liposomal membrane permeability assessment by fluorescence techniques: Main permeabilizing agents, applications and challenges

G Nasr, H Greige-Gerges, A Elaissari… - International Journal of …, 2020 - Elsevier
Liposomes are lipid vesicles made of one or multiple lipid bilayers surrounding an internal
aqueous core. They are broadly employed as models to study membrane structure and …

Lipid exchange envelope penetration (LEEP) of nanoparticles for plant engineering: a universal localization mechanism

MH Wong, RP Misra, JP Giraldo, SY Kwak, Y Son… - Nano …, 2016 - ACS Publications
Nanoparticles offer clear advantages for both passive and active penetration into
biologically important membranes. However, the uptake and localization mechanism of …

[HTML][HTML] New insights on the mechanism of polyethylenimine transfection and their implications on gene therapy and DNA vaccines

J Sabin, M Alatorre-Meda, J Miñones Jr… - Colloids and Surfaces B …, 2022 - Elsevier
Polyethylenimine (PEI) has been demonstrated as an efficient DNA delivery vehicle both in
vitro and in vivo. There is a consensus that PEI-DNA complexes enter the cells by …

Molecular mechanism of polycation-induced pore formation in biomembranes

N Awasthi, W Kopec, N Wilkosz, D Jamróz… - ACS Biomaterials …, 2018 - ACS Publications
Polycations are an attractive class of macromolecules with promising applications as
drug/gene carriers and biocides. The chemical structure and concentration of a polycation …

Interactions of polyethylenimines with zwitterionic and anionic lipid membranes

U Kwolek, D Jamróz, M Janiczek, M Nowakowska… - Langmuir, 2016 - ACS Publications
Interactions between polyethylenimines (PEIs) and phospholipid membranes are of
fundamental importance for various biophysical applications of these polymers such as …

Translocation mechanisms of cell-penetrating polymers identified by induced proton dynamics

T Goda, Y Imaizumi, H Hatano, A Matsumoto… - Langmuir, 2019 - ACS Publications
Unlike the majority of nanomaterials designed for cellular uptake via endocytic pathways,
some of the functional nanoparticles and nanospheres directly enter the cytoplasm without …

Effect of polycation structure on interaction with lipid membranes

N Wilkosz, D Jamróz, W Kopec, K Nakai… - The Journal of …, 2017 - ACS Publications
Interaction of polycations with lipid membranes is a very important issue in many biological
and medical applications such as gene delivery or antibacterial usage. In this work, we …

Characterization of conformation and interaction of gene delivery vector polyethylenimine with phospholipid bilayer at different protonation state

CK Choudhury, A Kumar, S Roy - Biomacromolecules, 2013 - ACS Publications
Polyethylenimine (PEI) is a pH sensitive polymer possessing stretched and coiled
conformation at low and high pH, respectively. It is an efficient gene delivery agent. Thus, the …

Interactions of a hydrophobically modified polycation with zwitterionic lipid membranes

M Kepczynski, D Jamróz, M Wytrwal, J Bednar… - Langmuir, 2012 - ACS Publications
The interactions between synthetic polycations and phospholipid bilayers play an important
role in some biophysical applications such as gene delivery or antibacterial usage. Despite …