Ecology and evolution of Mycobacterium tuberculosis

S Gagneux - Nature Reviews Microbiology, 2018 - nature.com
Tuberculosis (TB) is the number one cause of human death due to an infectious disease.
The causative agents of TB are a group of closely related bacteria known as the …

Non-tuberculous mycobacteria: Molecular and physiological bases of virulence and adaptation to ecological niches

AC Pereira, B Ramos, AC Reis, MV Cunha - Microorganisms, 2020 - mdpi.com
Non-tuberculous mycobacteria (NTM) are paradigmatic colonizers of the total environment,
circulating at the interfaces of the atmosphere, lithosphere, hydrosphere, biosphere, and …

Amoebae as training grounds for microbial pathogens

CTD Price, HE Hanford, T Al-Quadan, M Santic… - MBio, 2024 - journals.asm.org
Grazing of amoebae on microorganisms represents one of the oldest predator-prey dynamic
relationships in nature. It represents a genetic “melting pot” for an ancient and continuous …

Antimicrobial resistance in Mycobacterium tuberculosis: the odd one out

V Eldholm, F Balloux - Trends in microbiology, 2016 - cell.com
Antimicrobial resistance (AMR) threats are typically represented by bacteria capable of
extensive horizontal gene transfer (HGT). One clear exception is Mycobacterium …

The many lives of nontuberculous mycobacteria

TA Claeys, RT Robinson - 2018 - Am Soc Microbiol
Nontuberculous mycobacteria (NTM) include species that colonize human epithelia, as well
as species that are ubiquitous in soil and aquatic environments. NTM that primarily inhabit …

Genetic Diversity in Mycobacterium tuberculosis Clinical Isolates and Resulting Outcomes of Tuberculosis Infection and Disease

JS Peters, N Ismail, A Dippenaar, S Ma… - Annual Review of …, 2020 - annualreviews.org
Tuberculosis claims more human lives than any other bacterial infectious disease and
represents a clear and present danger to global health as new tools for vaccination …

Comparative genomics of Mycobacterium avium complex reveals signatures of environment-specific adaptation and community acquisition

EC Keen, JH Choi, MA Wallace, M Azar… - Msystems, 2021 - Am Soc Microbiol
Nontuberculous mycobacteria, including those in the Mycobacterium avium complex (MAC),
constitute an increasingly urgent threat to global public health. Ubiquitous in soil and water …

[HTML][HTML] Characteristics of subtype III-A CRISPR-Cas system in Mycobacterium tuberculosis: An overview

I Hamdi, F Boni, Q Shen, L Moukendza, L Peibo… - Infection, Genetics and …, 2023 - Elsevier
CRISPR-Cas systems are the only RNA-guided adaptive immunity pathways that trigger the
detection and destruction of invasive phages and plasmids in bacteria and archaea. Due to …

Genome-wide analysis of horizontally acquired genes in the genus Mycobacterium

A Panda, M Drancourt, T Tuller, P Pontarotti - Scientific reports, 2018 - nature.com
Horizontal gene transfer (HGT) was attributed as a major driving force for the innovation and
evolution of prokaryotic genomes. Previously, multiple research endeavors were undertaken …

Antimicrobial Resistance in Rapidly Growing Nontuberculous Mycobacteria among Domestic and Wild Animals Emphasizing the Zoonotic Potential

I Reil, S Špičić, L Barbić, S Duvnjak, G Kompes… - Microorganisms, 2023 - mdpi.com
Non-tuberculous mycobacteria (NTM) are opportunistic pathogens capable of causing
infections in humans and animals. The aim of this study was to demonstrate the potential …