Drug-induced liver injury (DILI) is a serious health burden. It has diverse clinical
presentations that can escalate to acute liver failure. The worldwide increase in the use of …

Background: Depression is considered as one of the most common neuropsychiatric
symptoms (NPS) in Alzheimer's disease (AD) patients. Prescription of antidepressants is a …

Cannabidiol (CBD) is one of the primary cannabinoids present in extracts of the plant
Cannabis sativa L. A CBD-based drug, Epidiolex, has been approved by the US FDA for the …

Sertraline is a commonly used SSRI antidepressant drug, metabolized by CYP2C19 and
CYP2B6, that exhibits a substantial interindividual variation in clinical response, of which …

Tire wear particles are a notable source of tire microplastics (TMPs) in the environment.
However, only a few reports have focused on the aquatic toxicity effects of composite TMPs …

Hepatic metabolism catalyzed by the cytochrome P450 (CYP) superfamily affects liver
toxicity associated with exposures to natural compounds and xenobiotic agents. Previously …

Cannabidiol (CBD) is one of the most prevalent and abundant cannabinoids extracted from
the plant Cannabis sativa. CBD has been reported to induce male reproductive toxicity in …

Gamma radiation was applied to degradation selected antidepressants in ultrapure water
and surface water. Additionally, the influence of typical radical scavengers like carbonate …

Cannabidiol (CBD), one of the major components extracted from the plant Cannabis sativa
L., has been used as a prescription drug to treat seizures in many countries. CBD-induced …

As the most prescribed psychotropic drugs in current medical practice, antidepressant drugs
(ADs) of the selective serotonin reuptake inhibitor (SSRI) class represent prime candidates …