Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by
the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells. IL-17A is …

IL-17 is a highly versatile pro-inflammatory cytokine crucial for a variety of processes,
including host defense, tissue repair, the pathogenesis of inflammatory disease and the …

Bacterial anti-phage systems are frequently clustered in microbial genomes, forming
defense islands. This property enabled the recent discovery of multiple defense systems …

Interleukin (IL)-17 is the founding member of a novel family of inflammatory cytokines. While
the proinflammatory properties of IL-17 are key to its host-protective capacity, unrestrained IL …

The IL-17/IL-17 receptor family is the newest and least understood of the cytokine
subclasses. Composed of ligands IL-17A-IL-17F and receptors IL-17RA-IL-17RE, these …

TLRs are a family of pattern recognition receptors that recognize conserved molecular
structures/products from a wide variety of microbes. Following recognition of ligands, TLRs …

Chronic mucocutaneous candidiasis (CMC) is defined as recurrent or persistent infection of
the skin, nails, and/or mucosae with commensal Candida species. The first genetic etiology …

Interleukin-17 (IL-17), the signature cytokine produced by T helper 17 (Th17) cells, plays
pivotal roles in host defense responses against microbial invasion, as well as in the …

Inflammation is the immediate protective response of the body to pathogen invasions,
allergen challenges, chemical exposures or physical injuries. Acute inflammation usually …

Systemic rheumatic diseases are a heterogeneous group of autoimmune disorders that
affect the connective tissue, characterized by the involvement of multiple organs, leading to …