Revisiting netrin-1: one who guides (axons)
NP Boyer, SL Gupton - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Proper patterning of the nervous system requires that developing axons find appropriate
postsynaptic partners; this entails microns to meters of extension through an extracellular …
postsynaptic partners; this entails microns to meters of extension through an extracellular …
Role of Netrin-1 signaling in nerve regeneration
XP Dun, DB Parkinson - International journal of molecular sciences, 2017 - mdpi.com
Netrin-1 was the first axon guidance molecule to be discovered in vertebrates and has a
strong chemotropic function for axonal guidance, cell migration, morphogenesis and …
strong chemotropic function for axonal guidance, cell migration, morphogenesis and …
Multi-trait analysis for genome-wide association study of five psychiatric disorders
We conducted a cross-trait meta-analysis of genome-wide association study on
schizophrenia (SCZ)(n= 65,967), bipolar disorder (BD)(n= 41,653), autism spectrum …
schizophrenia (SCZ)(n= 65,967), bipolar disorder (BD)(n= 41,653), autism spectrum …
Causal influences of neuroticism on mental health and cardiovascular disease
F Zhang, A Baranova, C Zhou, H Cao, J Chen, X Zhang… - Human genetics, 2021 - Springer
We investigated the relationship between neuroticism and 16 mental and 18 physical traits
using summary results of genome-wide association studies for these traits. LD score …
using summary results of genome-wide association studies for these traits. LD score …
Long neural genes harbor recurrent DNA break clusters in neural stem/progenitor cells
Repair of DNA double-strand breaks (DSBs) by non-homologous end joining is critical for
neural development, and brain cells frequently contain somatic genomic variations that …
neural development, and brain cells frequently contain somatic genomic variations that …
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain
Back pain is the# 1 cause of years lived with disability worldwide, yet surprisingly little is
known regarding the biology underlying this symptom. We conducted a genome-wide …
known regarding the biology underlying this symptom. We conducted a genome-wide …
A human IgSF cell-surface interactome reveals a complex network of protein-protein interactions
Cell-surface protein-protein interactions (PPIs) mediate cell-cell communication, recognition,
and responses. We executed an interactome screen of 564 human cell-surface and secreted …
and responses. We executed an interactome screen of 564 human cell-surface and secreted …
Making dopamine connections in adolescence
A dramatic maturational process ongoing in adolescence is prefrontal cortex development,
including its dopamine innervation. Dopamine axons grow from the striatum to the prefrontal …
including its dopamine innervation. Dopamine axons grow from the striatum to the prefrontal …
DCC confers susceptibility to depression-like behaviors in humans and mice and is regulated by miR-218
Backgroud Variations in the expression of the Netrin-1 guidance cue receptor DCC (deleted
in colorectal cancer) appear to confer resilience or susceptibility to psychopathologies …
in colorectal cancer) appear to confer resilience or susceptibility to psychopathologies …
Piezoelectric materials and systems for tissue engineering and implantable energy harvesting devices for biomedical applications
Recently, the development of smart materials and the study of their properties has provided
an innovative approach to the field of tissue engineering. Piezoelectrics, which are able to …
an innovative approach to the field of tissue engineering. Piezoelectrics, which are able to …