Plant molecular farming: A viable platform for recombinant biopharmaceutical production

B Shanmugaraj, CJ I. Bulaon, W Phoolcharoen - Plants, 2020 - mdpi.com
The demand for recombinant proteins in terms of quality, quantity, and diversity is increasing
steadily, which is attracting global attention for the development of new recombinant protein …

[HTML][HTML] Biotechnology applications of plant callus cultures

T Efferth - Engineering, 2019 - Elsevier
In ethnopharmacology, and especially in traditional Chinese medicine, medicinal plants
have been used for thousands of years. Similarly, agricultural plants have been used …

Expression of recombinant antibodies

A Frenzel, M Hust, T Schirrmann - Frontiers in immunology, 2013 - frontiersin.org
Recombinant antibodies are highly specific detection probes in research, diagnostics, and
have emerged over the last two decades as the fastest growing class of therapeutic proteins …

Plants and human health in the twenty-first century

I Raskin, DM Ribnicky, S Komarnytsky, N Ilic… - TRENDS in …, 2002 - cell.com
The concept of growing crops for health rather than for food or fiber is slowly changing plant
biotechnology and medicine. Rediscovery of the connection between plants and health is …

The production of recombinant pharmaceutical proteins in plants

JKC Ma, PMW Drake, P Christou - Nature reviews genetics, 2003 - nature.com
Imagine a world in which any protein, either naturally occurring or designed by man, could
be produced safely, inexpensively and in almost unlimited quantities using only simple …

[HTML][HTML] Natural bioactive products as promising therapeutics: A review of natural product-based drug development

CB Aware, DN Patil, SS Suryawanshi, PR Mali… - South African Journal of …, 2022 - Elsevier
Since ancient times, natural medicines have had paramount importance in bolstering
biotherapeutics to treat various diseases. The World Health Organization (WHO) revealed …

Molecular farming in plants: host systems and expression technology

RM Twyman, E Stoger, S Schillberg, P Christou… - TRENDS in …, 2003 - cell.com
Plants provide an inexpensive and convenient system for the large-scale production of
valuable recombinant proteins. This principle has been demonstrated by the commercial …

Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants

H Daniell, SJ Streatfield, K Wycoff - Trends in plant science, 2001 - cell.com
The use of plants for medicinal purposes dates back thousands of years but genetic
engineering of plants to produce desired biopharmaceuticals is much more recent. As the …

Plant cell cultures for the production of recombinant proteins

S Hellwig, J Drossard, RM Twyman, R Fischer - Nature biotechnology, 2004 - nature.com
The use of whole plants for the synthesis of recombinant proteins has received a great deal
of attention recently because of advantages in economy, scalability and safety compared …

Molecular farming of pharmaceutical proteins

R Fischer, N Emans - Transgenic research, 2000 - Springer
Molecular farming is the production of pharmaceutically important and commercially
valuable proteins in plants. Its purpose is to provide a safe and inexpensive means for the …