Biological responses to imazapic and methyl parathion pesticides in bioinspired lipid membranes and Tilapia fish

RJG Rubira, VRG Batista, RR Correia… - Journal of hazardous …, 2023 - Elsevier
Pesticide misuse has well-documented detrimental effects on ecosystems, with Nile tilapia
(Oreochromis niloticus) being particularly vulnerable. The current study focuses on the …

Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice

R Sharma, Y Ishimaru, I Davison, K Ikegami, MS Chien… - Elife, 2017 - elifesciences.org
Each of the olfactory sensory neurons (OSNs) chooses to express a single G protein-
coupled olfactory receptor (OR) from a pool of hundreds. Here, we show the receptor …

Structural instability and divergence from conserved residues underlie intracellular retention of mammalian odorant receptors

K Ikegami, CA de March, MH Nagai… - Proceedings of the …, 2020 - National Acad Sciences
Mammalian odorant receptors are a diverse and rapidly evolving set of G protein-coupled
receptors expressed in olfactory cilia membranes. Most odorant receptors show little to no …

Sequence coevolution and structure stabilization modulate olfactory receptor expression

S Ghosh, CA de March, S Branciamore, S Kaleem… - Biophysical …, 2022 - cell.com
Olfactory receptors (ORs) belong to class A G-protein coupled receptors (GPCRs) and are
activated by a variety of odorants. To date, there is no three-dimensional structure of an OR …

Odorant receptors can mediate axonal identity and gene choice via cAMP-independent mechanisms

K Movahedi, X Grosmaitre, P Feinstein - Open Biology, 2016 - royalsocietypublishing.org
Odorant receptors (ORs) control several aspects of cell fate in olfactory sensory neurons
(OSNs), including singular gene choice and axonal identity. The mechanisms of OR-induced …

Expression pattern and clinical significance of beta 2-adrenergic receptor in oral squamous cell carcinoma: an emerging prognostic indicator and future therapeutic …

A Krishna, V Singh, N Singh, S Singh… - Clinical and …, 2022 - Springer
Abstract Purpose Beta 2-Adrenergic Receptor (β2-AR) is significantly overexpressed in
various types of malignancies, which is associated with the worst prognosis. However, the …

[HTML][HTML] Rapid Degradation of the Human ACE2 Receptor Upon Binding and Internalization of SARS-Cov-2-Spike-RBD Protein

P Feinstein - bioRxiv, 2024 - ncbi.nlm.nih.gov
It is widely accepted that the SARS-CoV-2 betacoronavirus infects humans through binding
the human Angiotensin Receptor 2 (ACE2) that lines the nasal cavity and lungs, followed by …

[PDF][PDF] Divergence from conserved residues underlies intracellular retention of mammalian odorant receptors

K Ikegami, CA de March, MH Nagai, S Ghosh, M Do… - BioRxiv, 2019 - scholar.archive.org
Mammalian odorant receptors are a diverse group of G-protein coupled receptors
abundantly expressed in the olfactory cilia membrane. The vast majority of odorant receptors …

Interação entre modelos de biomembrana baseados em filmes de Langmuir e vesículas unilamelares gigantes (GUVs) com herbicidas triazínicos e detecção via …

RJG Rubira - 2020 - repositorio.unesp.br
1.1. Motivação De acordo com o decreto N 4.074 de 4 de janeiro de 2002, o Brasil define
“agrotóxico como sendo produtos e agentes de processos físicos, químicos ou biológicos …

Probing the Limits of Singular Gene Expression Through the Activity of High Representation Odorant Receptor Transgenes

E Lempert - 2020 - search.proquest.com
Singular gene expression is a common phenomenon in biology, making its appearance in
immunoglobulin selection, protocadherin expression, X chromosome-inactivation, random …