Oxidative stress in anxiety and comorbid disorders

I Hovatta, J Juhila, J Donner - Neuroscience research, 2010 - Elsevier
Anxiety disorders, depression, and alcohol use disorder are common neuropsychiatric
diseases that often occur together. Oxidative stress has been suggested to contribute to their …

Impact of social relationships on Alzheimer's memory impairment: mechanistic studies

YH Hsiao, CH Chang, PW Gean - Journal of biomedical science, 2018 - Springer
Alzheimer's disease (AD) is characterized by progressive memory and neuronal loss
culminating in cognitive impairment that not only affects a person's living ability but also …

Parvalbumin interneuron in the ventral hippocampus functions as a discriminator in social memory

X Deng, L Gu, N Sui, J Guo… - Proceedings of the …, 2019 - National Acad Sciences
The ability to identify strange conspecifics in societies is supported by social memory, which
is vital for gregarious animals and humans. The function of hippocampal principal neurons …

Checks and balances: The glucocorticoid receptor and NFĸB in good times and bad

M Bekhbat, SA Rowson, GN Neigh - Frontiers in neuroendocrinology, 2017 - Elsevier
Mutual regulation and balance between the endocrine and immune systems facilitate an
organism's stress response and are impaired following chronic stress or prolonged immune …

Increase of oxidation and inflammation in nervous and immune systems with aging and anxiety

C Vida, EM Gonzalez… - Current Pharmaceutical …, 2014 - ingentaconnect.com
According to the oxidation-inflammation theory of aging, chronic oxidative stress and
inflammatory stress situations (with higher levels of oxidant and inflammatory compounds …

Effects of chronic social isolation on Wistar rat behavior and brain plasticity markers

J Djordjevic, A Djordjevic, M Adzic, MB Radojcic - Neuropsychobiology, 2012 - karger.com
Chronic stress is a contributing risk factor in the development of psychiatric illnesses,
including depressive disorders. The mechanisms of their psychopathology are multifaceted …

Isolation housing exacerbates Alzheimer's disease-like pathophysiology in aged APP/PS1 mice

H Huang, L Wang, M Cao, C Marshall… - International Journal …, 2015 - academic.oup.com
Background: Alzheimer's disease is a neurodegenerative disease characterized by gradual
declines in social, cognitive, and emotional functions, leading to a loss of expected social …

Impaired glucocorticoid-mediated HPA axis negative feedback induced by juvenile social isolation in male rats

G Boero, MG Pisu, F Biggio, L Muredda, G Carta… - …, 2018 - Elsevier
We previously demonstrated that socially isolated rats at weaning showed a significant
decrease in corticosterone and adrenocorticotropic hormone (ACTH) levels, associated with …

[HTML][HTML] Exercise-induced changes in brain activity during memory encoding and retrieval after long-term bed rest

A Friedl-Werner, K Brauns, HC Gunga, S Kühn… - NeuroImage, 2020 - Elsevier
Episodic memory depends decisively on the hippocampus and the parahippocampal gyrus,
brain structures that are also prone to exercise-induced neuroplasticity and cognitive …

Region-specific impairments in parvalbumin interneurons in social isolation-reared mice

H Ueno, S Suemitsu, S Murakami, N Kitamura, K Wani… - Neuroscience, 2017 - Elsevier
Many neuropsychiatric disorders show localized dysfunction in specific cortical regions. The
mechanisms underlying such region-specific vulnerabilities are unknown. Post-mortem …