The evolving role of natural products in drug discovery

FE Koehn, GT Carter - Nature reviews Drug discovery, 2005 - nature.com
Natural products and their derivatives have historically been invaluable as a source of
therapeutic agents. However, in the past decade, research into natural products in the …

Exploring new targets and chemical space with affinity selection-mass spectrometry

R Prudent, DA Annis, PJ Dandliker… - Nature Reviews …, 2021 - nature.com
Affinity selection-mass spectrometry (AS-MS) is a high-throughput screening (HTS)
technique for drug discovery that enables rapid screening of large collections of compounds …

Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells

L Yi, Z Li, K Yuan, X Qu, J Chen, G Wang… - Journal of …, 2004 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus (SARS-CoV) is the pathogen of SARS,
which caused a global panic in 2003. We describe here the screening of Chinese herbal …

[图书][B] Natural products from plants

LJ Cseke, A Kirakosyan, PB Kaufman, S Warber… - 2016 - api.taylorfrancis.com
2008 NOMINEE The Council on Botanical and Horticultural Libraries Annual Award for a
Significant Work in Botanical or Horticultural Literature From medicinal, industrial, and …

[图书][B] Introduction to green chemistry

J Andraos, AS Matlack - 2022 - taylorfrancis.com
Interest in green chemistry and clean processes has grown so much in recent years that
topics such as fluorous biphasic catalysis, metal organic frameworks, and process …

Solid-phase oligosaccharide synthesis and combinatorial carbohydrate libraries

PH Seeberger, WC Haase - Chemical reviews, 2000 - ACS Publications
The transfer of information is a fundamental process of life and central to all cellular systems.
From a biological perspective, information needs to be transmitted intracellularly and …

[图书][B] Handbook of affinity chromatography

T Kline - 1993 - taylorfrancis.com
Outlining the fundamental principles by which all interactions occur, this reference focuses
on harnessing the biochemistry of bioorganic compounds in order to separate them …

[图书][B] Chromatography: Fundamentals and applications of chromatography and related differential migration methods-Part B: Applications

E Heftmann - 2004 - books.google.com
Chromatography has emerged as the most important and versatile analytical method. The
book is not only an updated version of Heftmann's classical text, but it covers areas of future …

The effect of the mobile phase additives on sensitivity in the analysis of peptides and proteins by high-performance liquid chromatography–electrospray mass …

MC García - Journal of Chromatography B, 2005 - Elsevier
The study of the effect of mobile phases on sensitivity in the analysis of peptides and
proteins by high-performance liquid chromatography (HPLC)–electrospray mass …

Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with …

O Potterat, M Hamburger - Natural product reports, 2013 - pubs.rsc.org
Covering: up to 2012Since the advent of high-throughput screening (HTS) in the early
1990s, a wealth of innovative technologies have been proposed and implemented for the …