A molecular imaging primer: modalities, imaging agents, and applications

ML James, SS Gambhir - Physiological reviews, 2012 - journals.physiology.org
Molecular imaging is revolutionizing the way we study the inner workings of the human
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …

Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

Prospective of 68Ga-radiopharmaceutical development

I Velikyan - Theranostics, 2013 - pmc.ncbi.nlm.nih.gov
Positron Emission Tomography (PET) experienced accelerated development and has
become an established method for medical research and clinical routine diagnostics on …

Photodynamic therapy and the development of metal‐based photosensitisers

LB Josefsen, RW Boyle - Metal‐Based Drugs, 2008 - Wiley Online Library
Photodynamic therapy (PDT) is a treatment modality that has been used in the successful
treatment of a number of diseases and disorders, including age‐related macular …

Clinical applications of Gallium-68

SR Banerjee, MG Pomper - Applied Radiation and Isotopes, 2013 - Elsevier
Gallium-68 is a positron-emitting radioisotope that is produced from a 68Ge/68Ga generator.
As such it is conveniently used, decoupling radiopharmacies from the need for a cyclotron …

Good practices for 68Ga radiopharmaceutical production

BJB Nelson, JD Andersson, F Wuest… - EJNMMI …, 2022 - Springer
Abstract Background The radiometal gallium-68 (68Ga) is increasingly used in diagnostic
positron emission tomography (PET), with 68Ga-labeled radiopharmaceuticals developed …

Bombesin functionalized gold nanoparticles show in vitro and in vivo cancer receptor specificity

N Chanda, V Kattumuri, R Shukla… - Proceedings of the …, 2010 - National Acad Sciences
Development of cancer receptor-specific gold nanoparticles will allow efficient
targeting/optimum retention of engineered gold nanoparticles within tumors and thus …

Technetium and gallium derived radiopharmaceuticals: comparing and contrasting the chemistry of two important radiometals for the molecular imaging era

MD Bartholoma, AS Louie, JF Valliant… - Chemical …, 2010 - ACS Publications
The objective of medical imaging using molecular probes and perfusion radiotracers is to
provide rapid, noninvasive evaluation of physiology, pathology, and/or organ function. The …

Imaging of neuroendocrine tumors

V Rufini, ML Calcagni, RP Baum - Seminars in nuclear medicine, 2006 - Elsevier
Neuroendocrine tumors (NETs) are rare neoplasms, which are characterized by the
presence of neuroamine uptake mechanisms and/or peptide receptors at the cell membrane …

68Ga‐PET: a powerful generator‐based alternative to cyclotron‐based PET radiopharmaceuticals

M Fani, JP André, HR Maecke - Contrast media & molecular …, 2008 - Wiley Online Library
PET (positron emission tomography) is a powerful diagnostic and imaging technique which
requires short‐lived positron emitting isotopes. The most commonly used are accelerator …