The impact of COVID-19 disease on platelets and coagulation

GD Wool, JL Miller - Pathobiology, 2021 - karger.com
Abstract Coronavirus disease 2019 (COVID-19) causes a spectrum of disease; some
patients develop a severe proinflammatory state which can be associated with a unique …

Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation

SX Gu, T Tyagi, K Jain, VW Gu, SH Lee… - Nature Reviews …, 2021 - nature.com
The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …

SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

S Zhang, Y Liu, X Wang, L Yang, H Li, Y Wang… - Journal of hematology & …, 2020 - Springer
Background Critically ill patients diagnosed with COVID-19 may develop a pro-thrombotic
state that places them at a dramatically increased lethal risk. Although platelet activation is …

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

ED Hottz, IG Azevedo-Quintanilha… - Blood, The Journal …, 2020 - ashpublications.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent pathogen
responsible for the coronavirus disease 2019 (COVID-19). Since its emergence, the novel …

Platelet gene expression and function in patients with COVID-19

BK Manne, F Denorme, EA Middleton… - Blood, The Journal …, 2020 - ashpublications.org
There is an urgent need to understand the pathogenesis of coronavirus disease 2019
(COVID-19). In particular, thrombotic complications in patients with COVID-19 are common …

COVID-19-associated coagulopathy and disseminated intravascular coagulation

H Asakura, H Ogawa - International journal of hematology, 2021 - Springer
The pathology of coronavirus disease 2019 (COVID-19) is exacerbated by the progression
of thrombosis, and disseminated intravascular coagulation (DIC), and cytokine storms. The …

Prognostic factors for severity and mortality in patients infected with COVID-19: A systematic review

A Izcovich, MA Ragusa, F Tortosa, MA Lavena Marzio… - PloS one, 2020 - journals.plos.org
Background and purpose The objective of our systematic review is to identify prognostic
factors that may be used in decision-making related to the care of patients infected with …

The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications

JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing global pandemic has presented a health emergency of unprecedented …

The role of biomarkers in diagnosis of COVID-19–A systematic review

M Kermali, RK Khalsa, K Pillai, Z Ismail, A Harky - Life sciences, 2020 - Elsevier
Aims As of the 28th April 2020, the COVID-19 pandemic has infiltrated over 200 countries
and affected over three million confirmed people. We review different biomarkers to evaluate …

Thrombosis risk associated with COVID-19 infection. A scoping review

F Al-Ani, S Chehade, A Lazo-Langner - Thrombosis research, 2020 - Elsevier
Background Infection by the 2019 novel coronavirus (COVID-19) has been reportedly
associated with a high risk of thrombotic complications. So far information is scarce and …