Dopamine (DA) transmission is governed by processes that regulate release from axonal
boutons in the forebrain and the somatodendritic compartment in midbrain, and by …

Although cells in many brain regions respond to reward, the cortical-basal ganglia circuit is
at the heart of the reward system. The key structures in this network are the anterior …

The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …

The classical biogenic amine neurotransmitters—dopamine, noradrenaline, and 5-
hydroxytryptamine—control a variety of functions including locomotion, autonomic function …

The dopamine transporter (DAT) transports extracellular dopamine into the intracellular
space contributing to the regulation of dopamine neurotransmission. A reduction of DAT …

Selective blockers of the norepinephrine transporter (NET) inhibit dopamine uptake in the
prefrontal cortex. This suggests that dopamine in this region is normally cleared by the …

Among the neurotransmitters involved in addiction, dopamine (DA) is clearly the best known.
The critical role of DA in addiction is supported by converging evidence that has been …

The dopamine transporter (DAT) critically regulates the duration of the cellular actions of
dopamine and the extent to which dopamine diffuses in the extracellular space. We sought …

Mutations in α‐synuclein, a protein highly enriched in presynaptic terminals, have been
implicated in the expression of familial forms of Parkinson's disease (PD) whereas native α …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by fibrillar neuronal
inclusions composed of aggregated α-synuclein (α-syn). These inclusions are associated …