Macrophages are versatile and heterogeneous innate immune cells undertaking central
functions in balancing immune responses and tissue repair to maintain homeostasis. This …

Chimeric antigen receptor-T (CAR-T) cell-based therapy has become a successful option for
treatment of numerous hematological malignancies, but also raises hope in a range of non …

Chimeric antigen receptor (CAR) T cell therapy has shown promising results in hematologic
malignancies, but its effectiveness in solid cancers remains challenging. Macrophages are …

Macrophages measure the" eat-me" signal immunoglobulin G (IgG) to identify targets for
phagocytosis. We tested whether prior encounters with IgG influence macrophage appetite …

Breast cancer is the most prevalent malignant neoplasm worldwide, necessitating the
development of novel therapeutic strategies owing to the limitations posed by conventional …

Generation of chimeric antigen receptor macrophages (CAR-Ms) from human pluripotent
stem cells (hPSCs) offers new prospects for cancer immunotherapy but is currently …