Junctional adhesion molecules (JAMs) of the immunoglobulin superfamily are important in
the control of vascular permeability and leukocyte transmigration across endothelial-cell …

The high prevalence of obesity, atherosclerosis, and cardiovascular disease (CVD) is
largely attributable to the contemporary lifestyle that is often sedentary and includes a diet …

Atherosclerosis is the underlying reason for nearly all causes of coronary artery disease and
peripheral arterial disease and many cases of stroke. Atherosclerosis is a systemic …

Cardiovascular diseases are the leading causes of mortality worldwide. Among them,
hypertension and its pathological complications pose a major risk for the development of …

Macrophages are heterogeneous and plastic cells, able to adapt their phenotype and
functions to changes in the microenvironment. They are involved in several homeostatic …

Background and Purpose—There is growing evidence suggesting that C-reactive protein
(CRP) is an effecter molecule able to induce and promote atherothrombosis. The presence …

Quercetin, the most abundant dietary flavonol, exerts vasodilator, anti-hypertensive, and anti-
atherogenic effects and reduces the vascular remodelling associated with elevated blood …

Plaque rupture and thrombosis are the most important clinical complications in the
pathogenesis of stroke, coronary arteries, and peripheral vascular diseases. The …

TNF receptor associated factors (TRAFs) represent a family of cytoplasmic signaling adaptor
proteins that regulate, bundle, and transduce inflammatory signals downstream of TNF-(TNF …

Background Formation of haemorrhagic neovessels in the intima of developing
atherosclerotic plaques is thought to significantly contribute to plaque instability resulting in …