Monoclonal antibodies blocking CGRP transmission: an update on their added value in migraine prevention

J Schoenen, M Manise, R Nonis, P Gérard… - Revue …, 2020 - Elsevier
The avenue of effective migraine therapies blocking calcitonin gene-related peptide (CGRP)
transmission is the successful outcome of 35 years of translational research. Developed …

Targeting CGRP for migraine treatment: mechanisms, antibodies, small molecules, perspectives

E De Matteis, M Guglielmetti, R Ornello… - Expert review of …, 2020 - Taylor & Francis
ABSTRACT Introduction Calcitonin Gene-Related Peptide (CGRP) has gradually emerged
as a suitable therapeutic target to treat migraine. Considering the social and economic …

Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders

A Segal, L Parkes, K Aquino, SM Kia, T Wolfers… - Nature …, 2023 - nature.com
The substantial individual heterogeneity that characterizes people with mental illness is
often ignored by classical case–control research, which relies on group mean comparisons …

Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation

T Tsuboi, JK Wong, RS Eisinger, L Okromelidze… - Brain, 2021 - academic.oup.com
The pathophysiology of dystonic tremor and essential tremor remains partially understood.
In patients with medication-refractory dystonic tremor or essential tremor, deep brain …

Abnormalities in resting-state EEG microstates are a vulnerability marker of migraine

Y Li, G Chen, J Lv, L Hou, Z Dong, R Wang… - The journal of headache …, 2022 - Springer
Background Resting-state EEG microstates are thought to reflect brief activations of several
interacting components of resting-state brain networks. Surprisingly, we still know little about …

Heterogeneous neuroimaging findings across substance use disorders localize to a common brain network

JL Stubbs, JJ Taylor, SH Siddiqi, FL Schaper… - Nature Mental …, 2023 - nature.com
Substance use disorders are associated with neuroimaging abnormalities, but results are
heterogeneous across studies and vary across substances, and the causal interpretation of …

Menstrually-related migraine shapes the structural similarity network integration of brain

X Li, H Hao, Y Li, LWC Au, G Du, X Gao, J Yan… - Cerebral …, 2023 - academic.oup.com
Menstrually-related migraine (MM) is a primary migraine in women of reproductive age. The
underlying neural mechanism of MM was still unclear. In this study, we aimed to reveal the …

Neuromodulation treatments for mild traumatic brain injury and post-concussive symptoms

A Mollica, R Greben, C Oriuwa, SH Siddiqi… - Current Neurology and …, 2022 - Springer
Abstract Purpose of Review Mild traumatic brain injury (mTBI) can result in prolonged post-
concussive symptoms (eg, depression, headaches, cognitive impairment) that are …

Genetic architecture underlying differential resting-state functional connectivity of subregions within the human visual cortex

C Zhang, H Cai, X Xu, Q Li, X Li, W Zhao… - Cerebral …, 2022 - academic.oup.com
The human visual cortex is a heterogeneous entity that has multiple subregions showing
substantial variability in their functions and connections. We aimed to identify genes …

The childhood migraine syndrome

I Abu-Arafeh, AA Gelfand - Nature Reviews Neurology, 2021 - nature.com
Migraine is a complex genetic brain disorder with an intricate pathogenesis and
polymorphous clinical presentations, particularly in children. In this Perspective, we describe …