Abstract Glycoside hydrolase family 18 (GH18) chitinases, which catalyze the
biodegradation of β-1, 4 glycosidic bond in amino polysaccharides via a substrate-assisted …

Chitinase (EC 3.2. 1.14) is an enzyme to breakdown β-1, 4-glycosidic bonds in chitin and
chitooligosaccharides. The loss of chitinase enzymatic activity in insects results in severe …

Fenoxaprop-p-ethyl (FE), a type of acetyl-CoA carboxylase (ACCase) inhibitor, has been
extensively applied to a variety of crop plants. It can cause damage to wheat (Triticum …

BACKGROUND Isoxaflutole (IXF), as a kind of 4‐hydroxyphenylpyruvate dioxygenase
(HPPD) inhibitor, has been widely used in many kinds of plants. IXF can cause injury in corn …

Multitarget inhibitors of insect chitinolytic enzymes are promising sources of green
insecticides. Machine learning (ML) is an emerging virtual screening method that can …

To discover fungicides with novel targets, a series of N-acyl-1, 2, 3, 4-tetrahydroquinoline
(NATHQ) derivatives were designed and synthesized by linking the active substructure …

Insect growth regulators (IGRs) are important insecticides that reduce the harm caused by
insects to crops by controlling pest population growth. Chitinases are closely associated with …

Asian corn borer (Ostrinia furnacalis) is one of the most destructive pests in agriculture.
Three chitinases Of ChtI, Of ChtII, and Of Chi-h are regarded as potential targets for …

The insect chitinase Of ChtI from the agricultural pest Ostrinia furnacalis (Asian corn borer) is
a promising target for green insecticide design. Of ChtI is a critical chitinolytic enzyme for the …

Nematode chitinases are critical components of the nematode life cycle, and Ce Cht1 is a
potential target for developing novel nematicides. Herein, lunidonine, a natural quinoline …