The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …

The nutraceuticals market is vast, encompassing many different products with inconsistent
levels of evidence available to support their use. This overview represents a Western …

Major depressive disorder (MDD) is a debilitating illness characterized by neuroanatomical
and functional alterations in limbic structures, notably the prefrontal cortex (PFC), that can be …

Cannabis has a long history of medical use. Although there are many cannabinoids present
in cannabis, Δ9tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two …

Mood disorders are the most prevalent mental conditions encountered in psychiatric
practice. Numerous patients suffering from mood disorders present with treatment-resistant …

Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …

Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …

With the increasing push to legalize cannabis in Western nations, there is a need to gage
the potential impact of this policy change on vulnerable populations, such as those with …

Context: Chronic pain is highly prevalent in most of the industrialized nations around the
world. Despite the documented adverse effects, opioids are widely used for pain …