An update on the anticancer activity of xanthone derivatives: A review

YS Kurniawan, KTA Priyangga, Jumina, HD Pranowo… - Pharmaceuticals, 2021 - mdpi.com
The annual number of cancer deaths continues increasing every day; thus, it is urgent to
search for and find active, selective, and efficient anticancer drugs as soon as possible …

From natural products to new synthetic small molecules: A journey through the world of xanthones

MMM Pinto, A Palmeira, C Fernandes, DISP Resende… - Molecules, 2021 - mdpi.com
This work reviews the contributions of the corresponding author (MMMP) and her research
group to Medicinal Chemistry concerning the isolation from plant and marine sources of …

Recent insight into the biological activities of synthetic xanthone derivatives

I Ahmad - European journal of medicinal chemistry, 2016 - Elsevier
Xanthones are a class of oxygen containing heterocyclic compounds with a broad range of
biological activities, and they have prominent significance in the field of medicinal chemistry …

Liquid chromatography on the different methods for the determination of lipophilicity: An essential analytical tool in medicinal chemistry

JX Soares, Á Santos, C Fernandes, MMM Pinto - Chemosensors, 2022 - mdpi.com
Lipophilicity is one of many parameters involved in the biological activity of drugs, as it
affects their pharmacokinetic and pharmacodynamic behavior. Generally, lipophilicity is …

Recent advances in the synthesis of xanthones and azaxanthones

DISP Resende, F Durães, M Maia, E Sousa… - Organic Chemistry …, 2020 - pubs.rsc.org
Xanthones are important O-heteroaromatic tricyclic molecules exhibiting a wide range of
bioactivities and can represent a showcase to highlight the recent techniques and strategies …

Xanthones: biosynthesis and trafficking in plants, fungi and lichens

C Badiali, V Petruccelli, E Brasili, G Pasqua - Plants, 2023 - mdpi.com
Xanthones are a class of secondary metabolites produced by plant organisms. They are
characterized by a wide structural variety and numerous biological activities that make them …

Synthesis and molecular docking studies of xanthone attached amino acids as potential antimicrobial and anti-inflammatory agents

X Chen, J Leng, KP Rakesh, N Darshini… - …, 2017 - pubs.rsc.org
A series of novel xanthone conjugated amino acids were synthesised and characterised by
analytical and spectroscopic methods. All the synthesized analogues (2–23) were screened …

Chiral derivatives of xanthones with antimicrobial activity

J Araújo, C Fernandes, M Pinto, ME Tiritan - Molecules, 2019 - mdpi.com
According to the World Health Organization, the exacerbated use of antibiotics worldwide is
increasing multi-resistant infections, especially in the last decade. Xanthones are a class of …

Synthetic chiral derivatives of xanthones: Biological activities and enantioselectivity studies

C Fernandes, ML Carraro, J Ribeiro, J Araújo… - Molecules, 2019 - mdpi.com
Many naturally occurring xanthones are chiral and present a wide range of biological and
pharmacological activities. Some of them have been exhaustively studied and subsequently …

Chiral stationary phases based on small molecules: An update of the last 17 years

C Fernandes, YZ Phyo, AS Silva… - Separation & …, 2018 - Taylor & Francis
A literature survey covering the report on Pirkle-type chiral stationary phases (CSPs) from
January 2000 to March 2017 is presented in this review. More than 200 CSPs comprising …