Tolerance and Resistance of Pseudomonas aeruginosa Biofilms to Antimicrobial Agents—How P. aeruginosa Can Escape Antibiotics

O Ciofu, T Tolker-Nielsen - Frontiers in microbiology, 2019 - frontiersin.org
Pseudomonas aeruginosa is one of the six bacterial pathogens, Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …

Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria

CW Hall, TF Mah - FEMS microbiology reviews, 2017 - academic.oup.com
Biofilms are surface-attached groups of microbial cells encased in an extracellular matrix
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …

The role of reactive oxygen species in antibiotic-mediated killing of bacteria

H Van Acker, T Coenye - Trends in microbiology, 2017 - cell.com
Recently, it was proposed that there is a common mechanism behind the activity of
bactericidal antibiotics, involving the production of reactive oxygen species (ROS). However …

Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies

C De la Fuente-Núñez, F Reffuveille… - Current opinion in …, 2013 - Elsevier
Highlights•Biofilms may have evolved as an adaptive response to environmental
stresses.•Biofilm formation is a complex process involving sophisticated regulatory …

Broad-spectrum anti-biofilm peptide that targets a cellular stress response

C De la Fuente-Núñez, F Reffuveille, EF Haney… - PLoS …, 2014 - journals.plos.org
Bacteria form multicellular communities known as biofilms that cause two thirds of all
infections and demonstrate a 10 to 1000 fold increase in adaptive resistance to conventional …

The role of extracellular DNA in the establishment, maintenance and perpetuation of bacterial biofilms

M Okshevsky, RL Meyer - Critical reviews in microbiology, 2015 - Taylor & Francis
The significance of extracellular DNA (eDNA) in biofilms was overlooked until researchers
added DNAse to a Pseudomonas aeruginosa biofilm and watched the biofilm disappear …

[HTML][HTML] Pseudomonas aeruginosa biofilms and their partners in crime

M del Mar Cendra, E Torrents - Biotechnology advances, 2021 - Elsevier
Pseudomonas aeruginosa biofilms and the capacity of the bacterium to coexist and interact
with a broad range of microorganisms have a substantial clinical impact. This review focuses …

Antimicrobial effect of titanium dioxide nanoparticles

CL de Dicastillo, MG Correa, FB Martínez… - … Resistance-A One …, 2020 - books.google.com
The widespread use of antibiotics has led to the emergence of multidrugresistant bacterial
strains, and therefore a current concern for food safety and human health. The interest for …

Understanding the antimicrobial mechanism of TiO2-based nanocomposite films in a pathogenic bacterium

A Kubacka, MS Diez, D Rojo, R Bargiela, S Ciordia… - Scientific reports, 2014 - nature.com
Abstract Titania (TiO2)-based nanocomposites subjected to light excitation are remarkably
effective in eliciting microbial death. However, the mechanism by which these materials …

Bacterial stress responses as determinants of antimicrobial resistance

K Poole - Journal of Antimicrobial Chemotherapy, 2012 - academic.oup.com
Bacteria encounter a myriad of stresses in their natural environments, including, for
pathogens, their hosts. These stresses elicit a variety of specific and highly regulated …