Small-angle scattering (SAS) is a technique that is able to probe the structural organization
of matter and quantify its response to changes in external conditions. X-ray and neutron …

There is great need for stand-alone luminescence-based chemosensors that exemplify
selectivity, sensitivity, and applicability and that overcome the challenges that arise from …

Chiral plasmonic nanomaterials have attracted unprecedented attention due to their broad
applications in biomedicine, negative refractive index, and chiral sensing. Here, using a wet …

Hydrogen bonding interactions are ubiquitous across the biochemical and chemical
sciences, and are of particular interest to supramolecular chemists. They have been used to …

Antibodies protect from infection, underpin successful vaccines and elicit therapeutic
responses in otherwise untreatable cancers and autoimmune conditions. The human IgG2 …

X-ray crystallography enables detailed structural studies of proteins to understand and
modulate their function. Conducting crystallographic experiments at cryogenic temperatures …

Over the past several years, single-particle cryo-electron microscopy (cryo-EM) has
emerged as a leading method for elucidating macromolecular structures at near-atomic …

Protein structural biology came a long way since the determination of the first three-
dimensional structure of myoglobin about six decades ago. Across this period, X-ray …

Supramolecular peptide chemistry offers a versatile strategy to create chemical systems
useful as new biomaterials with potential to deliver nearly 1000 known candidate peptide …

Cobalamin-dependent methionine synthase (MetH) catalyzes the synthesis of methionine
from homocysteine and 5-methyltetrahydrofolate (CH3-H4folate) using the unique chemistry …