Metabolic engineering of Escherichia coli: a sustainable industrial platform for bio-based chemical production

X Chen, L Zhou, K Tian, A Kumar, S Singh… - Biotechnology …, 2013 - Elsevier
In order to decrease carbon emissions and negative environmental impacts of various
pollutants, more bulk and/or fine chemicals are produced by bioprocesses, replacing the …

Transcription regulation mechanisms of bacteriophages: recent advances and future prospects

H Yang, Y Ma, Y Wang, H Yang, W Shen, X Chen - Bioengineered, 2014 - Taylor & Francis
Phage diversity significantly contributes to ecology and evolution of new bacterial species
through horizontal gene transfer. Therefore, it is essential to understand the mechanisms …

Genetic engineering of Escherichia coli to improve L-phenylalanine production

Y Liu, Y Xu, D Ding, J Wen, B Zhu, D Zhang - BMC biotechnology, 2018 - Springer
Abstract Background L-phenylalanine (L-Phe) is an essential amino acid for mammals and
applications expand into human health and nutritional products. In this study, a system level …

Metabolic engineering of Escherichia coli for the production of cinnamaldehyde

HB Bang, YH Lee, SC Kim, CK Sung, KJ Jeong - Microbial cell factories, 2016 - Springer
Background Plant parasitic nematodes are harmful to agricultural crops and plants, and may
cause severe yield losses. Cinnamaldehyde, a volatile, yellow liquid commonly used as a …

Sequencing-based screening of functional microorganism to decrease the formation of biogenic amines in Chinese rice wine

SP Liu, JX Yu, XL Wei, ZW Ji, ZL Zhou, XY Meng… - Food Control, 2016 - Elsevier
As a traditional alcoholic beverage, Chinese rice wine with a unique flavor and high
nutritional value has been popular in China for thousands of years. The biogenic amines in …

Production of L-phenylalanine from glucose by metabolic engineering of wild type Escherichia coli W3110

SP Liu, MR Xiao, L Zhang, J Xu, ZY Ding, ZH Gu… - Process …, 2013 - Elsevier
The market of l-phenylalanine has been stimulated by the great demand for the low-calorie
sweetener aspartame. In this paper, the effects of pivotal genes on l-phenylalanine …

A systems level engineered E. coli capable of efficiently producing L-phenylalanine

SP Liu, RX Liu, MR Xiao, L Zhang, ZY Ding, ZH Gu… - Process …, 2014 - Elsevier
The biosynthesis of L-phenylalanine (Phe) is one of the most complicated amino acid
synthesis pathways. In this study, the engineering of Phe producer was carried out to …

Systematic engineering enables efficient biosynthesis of L-phenylalanine in E. coli from inexpensive aromatic precursors

M Nie, J Wang, Z Chen, C Cao, K Zhang - Microbial cell factories, 2024 - Springer
Background L-phenylalanine is an essential amino acid with various promising applications.
The microbial pathway for L-phenylalanine synthesis from glucose in wild strains involves …

Expanding the repertoire of aromatic chemicals by microbial production

F Wu, P Cao, G Song, W Chen… - Journal of Chemical …, 2018 - Wiley Online Library
Microbial production of aromatic chemicals would greatly contribute to solving the problems
with fossil resource supply and environmentally sustainable development. Engineering and …

Metabolic engineering for the production of l-phenylalanine in Escherichia coli

X Liu, H Niu, Q Li, P Gu - 3 Biotech, 2019 - Springer
As one of the three proteinogenic aromatic amino acids, l-phenylalanine is widely applied in
the food, chemical and pharmaceutical industries, especially in production of the low-calorie …