[HTML][HTML] Roles of endoplasmic reticulum stress in immune responses

JS So - Molecules and cells, 2018 - Elsevier
The endoplasmic reticulum (ER) is a critical organelle for protein synthesis, folding and
modification, and lipid synthesis and calcium storage. Dysregulation of ER functions leads to …

Endoplasmic reticulum stress induced by toxic elements—a review of recent developments

SVS Rana - Biological Trace Element Research, 2020 - Springer
Endoplasmic reticulum of all eukaryotic cells is a membrane-bound organelle. Under
electron microscope it appears as parallel arrays of “rough membranes” and a maze of …

The emerging roles of endoplasmic reticulum stress in balancing immunity and tolerance in health and diseases: mechanisms and opportunities

A Li, NJ Song, BP Riesenberg, Z Li - Frontiers in immunology, 2020 - frontiersin.org
The endoplasmic reticulum (ER) is an organelle equipped with mechanisms for proper
protein folding, trafficking, and degradation to maintain protein homeostasis in the secretory …

Protein-rich foods, sea foods, and gut microbiota amplify immune responses in chronic diseases and cancers–Targeting PERK as a novel therapeutic strategy for …

F Saaoud, Y Lu, K Xu, Y Shao, D Praticò… - Pharmacology & …, 2024 - Elsevier
The endoplasmic reticulum (ER) is a cellular organelle that is physiologically responsible for
protein folding, calcium homeostasis, and lipid biosynthesis. Pathological stimuli such as …

Vitexin Mitigates Staphylococcus aureus‐Induced Mastitis via Regulation of ROS/ER Stress/NF‐κB/MAPK Pathway

Y Chen, J Yang, Z Huang, B Yin, T Umar… - Oxidative Medicine …, 2022 - Wiley Online Library
Mastitis, caused by a variety of pathogenic microorganisms, seriously threatens the safety
and economic benefits of the dairy industry. Vitexin, a flavone glucoside found in many plant …

Cell-free DNA in plasma as an essential immune system regulator

M Korabecna, A Zinkova, I Brynychova, B Chylikova… - Scientific reports, 2020 - nature.com
The cell-free DNA (cfDNA) is always present in plasma, and it is biomarker of growing
interest in prenatal diagnostics as well as in oncology and transplantology for therapy …

Geraniol-mediated suppression of endoplasmic reticulum stress protects against cerebral ischemia–reperfusion injury via the PERK-ATF4-CHOP pathway

Y Wu, X Fan, S Chen, L Deng, L Jiang, S Yang… - International Journal of …, 2022 - mdpi.com
Endoplasmic reticulum (ER) stress plays an important role in cerebral ischemia–reperfusion
injury (CIRI). Geraniol has antioxidant, antibacterial, and anti-inflammatory activities. Studies …

Bushen Jieyu Tiaochong Formula reduces apoptosis of granulosa cells via the PERK-ATF4-CHOP signaling pathway in a rat model of polycystic ovary syndrome with …

X Pan, Y Liu, L Liu, B Pang, Z Sun, S Guan… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Polycystic ovary syndrome (PCOS) is a common and
complex endocrine disorder that is also an important cause of infertility. Adverse …

Marsdenia tenacissima extract induces endoplasmic reticulum stress-associated immunogenic cell death in non-small cell lung cancer cells through targeting AXL

Y Yuan, Y Guo, ZW Guo, HF Hao, YN Jiao… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Marsdenia Tenacissima (Roxb.) Wight et Arn. is a
traditional Chinese medicine. Its standardized extract (MTE), with the trade name Xiao-Ai …

Astaxanthin treatment ameliorates ER stress in polycystic ovary syndrome patients: A randomized clinical trial

M Jabarpour, A Aleyasin, MS Nashtaei, S Lotfi… - Scientific Reports, 2023 - nature.com
Astaxanthin (ASX), as a natural carotenoid compound, exists in various types of seafood and
microorganisms. It has several possible beneficial therapeutic effects for patients with …