Acute kidney injury (AKI) is a global public health concern associated with high morbidity
and mortality. Although advances in medical management have improved the in-hospital …

Chinese herbal medicine has been practiced for the prevention, treatment, and cure of
diseases for thousands of years. Herbal medicine involves the use of natural compounds …

Dyslipidemia is a common nutritional and metabolic disorder in patients with chronic kidney
disease. Accumulating evidence supports the hypothesis that prolonged metabolic …

Lipotoxicity is characterized by the ectopic accumulation of lipids in organs different from
adipose tissue. Lipotoxicity is mainly associated with dysfunctional signaling and insulin …

The rapid growth of obesity worldwide has made it a major health problem, while the
dramatic increase in the prevalence of obesity has had a significant impact on the …

The kidney is a highly metabolic organ and uses high levels of ATP to maintain electrolyte
and acid-base homeostasis and reabsorb nutrients. Energy depletion is a critical factor in …

Background and Purpose Disordered lipid metabolism and disturbed mitochondrial
bioenergetics play pivotal roles in the initiation and development of diabetic kidney disease …

Renal proximal tubular cells are the most energy-demanding cells in the body. The ATP that
they use is mostly produced in their mitochondrial and peroxisomal compartments, by the …

Free fatty acids (FFAs) play numerous vital roles in the organism, such as contribution to
energy generation and reserve, serving as an essential component of the cell membrane, or …

Recent evidence suggests potential benefits from phytochemicals and micronutrients in
reducing the elevated oxidative and lipid‐mediated stress associated with inflammation …