The first echinocandin-type antimycotic (echinocandin B) was discovered in the 1970s. It
was followed by the isolation of more than 20 natural echinocandins. These cyclic lipo …

In many Gram-negative pathogens, their virulent behavior is regulated by quorum sensing,
in which diffusible signals such as N-acyl homoserine lactones (AHLs) act as chemical …

It is of great importance to study the physiological roles of enzymes in nature; however, in
some cases, it is not easily apparent. Penicillin acylases are pharmaceutically important …

Biofilms represent an essential way of life and colonization of new environments for
microorganisms. This feature is regulated by quorum sensing (QS), a microbial …

Soil contamination by heavy metals, particularly mercury (Hg), is a problem that can
seriously affect the environment, animals, and human health. Hg has the capacity to …

Background Secondary metabolites as natural products from endophytic fungi are important
sources of pharmaceuticals. However, there is currently little understanding of endophytic …

Many Gram-negative bacteria produce N-acyl-homoserine lactones (AHLs), quorum sensing
(QS) molecules that can be enzymatically inactivated by quorum quenching (QQ) processes; …

Streptomyces sp. strain K30 induces the formation of an extracellular Lcp (latex‐clearing
protein) during poly (cis‐1, 4‐isoprene) degradation. To investigate the function of this …

Actinoplanes utahensis deacylase (AAC)-catalyzed deacylation of echinocandin B (ECB) is
a promising method for the synthesis of anidulafungin, the newest of the echinocandin …

Many intercellular communication processes, known as quorum sensing (QS), are regulated
by the autoinducers N-acyl-l-homoserine lactones (AHLs) in Gram-negative bacteria. The …