Pulmonary phenotypes of bronchopulmonary dysplasia in the preterm infant

M Gilfillan, V Bhandari - Seminars in perinatology, 2023 - Elsevier
Bronchopulmonary dysplasia (BPD) remains the most common complication of premature
birth, imposing a significant and potentially life-long burden on patients and their families …

Reinitiating lung development: a novel approach in the management of bronchopulmonary dysplasia

X Cui, J Fu - Respiratory Research, 2024 - Springer
Bronchopulmonary dysplasia (BPD) is the predominant chronic lung disease in preterm
infants, linked with various adverse long-term outcomes. Multiple prenatal and postnatal risk …

Amniotic fluid stem cell extracellular vesicles promote lung development via TGF-beta modulation in a fetal rat model of oligohydramnios

F Doktor, RL Figueira, V Fortuna, G Biouss… - Journal of Controlled …, 2025 - Elsevier
Oligohydramnios (decreased amniotic fluid volume for gestational age) is a severe condition
associated with high morbidity and mortality mainly due to fetal pulmonary hypoplasia …

Opposing roles for TGFβ-and BMP-signaling during nascent alveolar differentiation in the developing human lung

T Frum, PP Hsu, RFC Hein, AS Conchola… - NPJ Regenerative …, 2023 - nature.com
Abstract Alveolar type 2 (AT2) cells function as stem cells in the adult lung and aid in repair
after injury. The current study aimed to understand the signaling events that control …

Four markers useful for the distinction of intrauterine growth restriction in sheep

W Wang, S Chen, L Qiao, S Zhang, Q Liu, K Yang… - Animals, 2023 - mdpi.com
Simple Summary Intrauterine growth restriction (IUGR) is a disruption in the development of
animal embryos or fetal organs in the maternal uterus and is highly regarded because of its …

Impaired myofibroblast proliferation is a central feature of pathologic post-natal alveolar simplification

IS Khan, C Molina, X Ren, VC Auyeung, M Cohen… - eLife, 2024 - elifesciences.org
Premature infants with bronchopulmonary dysplasia (BPD) have impaired alveolar gas
exchange due to alveolar simplification and dysmorphic pulmonary vasculature. Advances …

Bronchopulmonary dysplasia demonstrates dysregulated autotaxin/lysophosphatidic acid signaling in a neonatal mouse model

AW Ha, T Sudhadevi, A Jafri, C Mayer… - Pediatric …, 2024 - nature.com
Background Bronchopulmonary dysplasia (BPD) is a chronic lung disease affecting
premature infants who require oxygen supplementation and ventilator therapy to support …

[HTML][HTML] Evidence for Wnt signaling's central involvement in perinatal nicotine exposure-induced offspring lung pathology and its modulation by electroacupuncture

Y Ge, Y Liu, B Ji, Y Fang, Y Xie, R Sakurai… - Biomedicine & …, 2023 - Elsevier
Objective Many factors during pregnancy can induce intrauterine growth restriction (IUGR),
resulting in various adverse perinatal outcomes such as low birth weight and multiple organ …

[HTML][HTML] Cadmium-induced Carcinogenesis in Respiratory Organs and the Prostate: Insights from Three Perspectives on Toxicogenomic Approach

J Lee, DY Shin, Y Jang, JP Han, EM Cho… - Journal of Cancer …, 2023 - ncbi.nlm.nih.gov
Cadmium (Cd) exposure primarily occurs through inhalation, either by smoking or
occupational exposure to contaminated air. Upon inhalation, Cd ultimately reaches the …

TSPYL1 as a Critical Regulator of TGFβ Signaling through Repression of TGFBR1 and TSPYL2

H Tan, MX Miao, RX Luo, J So, L Peng, X Zhu… - Advanced …, 2024 - Wiley Online Library
Nucleosome assembly proteins (NAPs) have been identified as histone chaperons. Testis‐
Specific Protein, Y‐Encoded‐Like (TSPYL) is a newly arisen NAP family in mammals …