Role of docking in anticancer drug discovery

A Alavi, V Sharma - Letters in Drug Design & Discovery, 2023 - benthamdirect.com
The computational method is widely used in the field of drug design as well as discovery. It
aids the drug discovery and design process by making the procedure faster while also …

Anti-obesity, antioxidant and in silico evaluation of Justicia carnea bioactive compounds as potential inhibitors of an enzyme linked with obesity: Insights from kinetics …

AA Anigboro, OJ Avwioroko, O Akeghware… - Biophysical …, 2021 - Elsevier
Obesity is a global health problem characterized by excessive fat deposition in adipose
tissues and can be managed by targeting pancreatic lipase (PL) activity. In the present …

The soursop (Annona muricata): Botany, horticulture, and utilization

F Leal, RE Paull - Crop Science, 2023 - Wiley Online Library
Abstract The South American soursop, guanabana or graviola fruit, was unknown to
Europeans until the voyages of Christopher Columbus. The tree is now grown commercially …

[HTML][HTML] Structure-based in silico investigation of antagonists of human ribonucleotide reductase from Annona muricata

DA Omoboyowa, DS Bodun, JA Saliu - Informatics in Medicine Unlocked, 2023 - Elsevier
Human ribonucleotide reductase (HRR) also known as ribonuceotide diphosphate
reductase catalyzes the conversion of ribonucleotide to deoxyribonuceotides which is the …

[HTML][HTML] Alpha-glucosidase activity of phytochemicals from Phyllanthus amarus leaves via in-silico approaches

AK Oyebamiji, EA Soetan, SA Akintelu… - Pharmacological …, 2022 - Elsevier
Diabetes mellitus is a metabolic disease that poses a serious global health challenge. The
provision of alternative and complementary medicine to combat the disease has attracted …

[PDF][PDF] Molecular modeling insights into bioactivities of Head-to-tail cyclic peptides: potential sedoheptulose-7-Phosphate isomerase inhibitors

AK Oyebamiji, SA Akintelu, B Semire… - Advanced Journal of …, 2024 - sid.ir
Burkholderia pseudomallei is the Gram-negative bacterium that cause infection termed
“Melioidosis”[ 1, 2]. It widely dominates soil as well as water surface and could easily be …

Protective Effect of Annona muricata Linn Fruit Pulp Lyophilized Powder against Paracetamol-Induced Redox Imbalance and Hepatotoxicity in Rats

S Menon, RA Al-Eisa, H Hamdi, L Lawrence… - Processes, 2023 - mdpi.com
In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was
evaluated for its hepatoprotective activity induced by paracetamol or acetaminophen …

[HTML][HTML] Inhibition of angiotensin converting enzyme by phytochemicals in Cucurbita pepo L.: In silico Approach

AM Oke, AO Adelakun, SA Akintelu, EA Soetan… - Pharmacological …, 2022 - Elsevier
Abstracts Diabetes mellitus remains one of the dreaded diseases that affect both man and
woman. It also causes a disorder which incapacitates human body from producing and …

[PDF][PDF] QSAR and molecular docking studies on nitro (triazole/imidazole)-based compounds as anti-tubercular agents

EA Erazua, SA Akintelu, JM Adelowo… - Tropical Journal of …, 2021 - researchgate.net
This work is aimed at identifying descriptors that described the anti-Mycobacterium
tuberculosis H37Rv activity of nitro (triazole/imidazole)-based compounds and reliable …

Biological evaluation of selected metronidazole derivatives as anti-nitroreductase via in silico approach

MD Adeoye, AK Oyebamiji, MA Ashiru… - Eclética …, 2022 - revista.iq.unesp.br
Abstract The 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole (2HMN) is a powerful
antibacterial and antiparasitic drug used alongside other drugs against Helicobacter pylori …