Restrictive vs liberal transfusion strategy in patients with acute brain injury: the TRAIN randomized clinical trial

FS Taccone, CR Bittencourt, K Møller, P Lormans… - Jama, 2024 - jamanetwork.com
Importance Blood transfusions are commonly administered to patients with acute brain
injury. The optimal hemoglobin transfusion threshold is uncertain in this patient population …

Tranexamic acid in patients undergoing liver resection: the HeLiX randomized clinical trial

PJ Karanicolas, Y Lin, SA McCluskey, J Tarshis… - JAMA, 2024 - jamanetwork.com
Importance Tranexamic acid reduces bleeding and blood transfusion in many types of
surgery, but its effect in patients undergoing liver resection for a cancer-related indication …

[HTML][HTML] Red Blood Cell Transfusion in Critically Ill Adults: An American College of Chest Physicians Clinical Practice Guideline

AOC Yataco, I Soghier, PC Hébert, E Belley-Cote… - Chest, 2024 - Elsevier
Background Blood products frequently are administered to critically ill patients. Considering
recent trials and practice variability, a comprehensive review of current evidence was …

How low can you go: Restrictive transfusion strategies in major surgery and physiological triggers

GMT Hare, A Alli, H Jiang, CD Mazer - Best Practice & Research Clinical …, 2023 - Elsevier
Anemia and red blood cell transfusion are associated with adverse outcomes. Large
randomized trials have demonstrated that restrictive transfusion strategies can safely reduce …

Blood, Bleeding, and Transfusion—A Theme Issue

CW Seymour - JAMA, 2023 - jamanetwork.com
More than 16 million units of blood are transfused in the US each year. 1 Blood transfusion
is a cornerstone of modern medicine and far from a new idea. The first successful human …

Haemoglobin values, transfusion practices, and long-term outcomes in critically ill patients with traumatic brain injury: a secondary analysis of CENTER-TBI

A Guglielmi, F Graziano, EG Bogossian, AF Turgeon… - Critical Care, 2024 - Springer
Haemoglobin (Hb) thresholds and red blood cells (RBC) transfusion strategies in traumatic
brain injury (TBI) are controversial. Our objective was to assess the association of Hb values …

Plasma transfusion in the intensive care unit

MMT van Haeren, SJ Raasveld, S de Bruin… - …, 2024 - Wiley Online Library
Background Current guidelines discourage prophylactic plasma use in non‐bleeding
patients. This study assesses global plasma transfusion practices in the intensive care unit …

[HTML][HTML] A Contemporary Review of Blood Transfusion in Critically Ill Patients

SK Yadav, G Hussein, B Liu, N Vojjala, M Warsame… - Medicina, 2024 - mdpi.com
Blood transfusion is a common therapeutic intervention in hospitalized patients. There are
numerous indications for transfusion, including anemia and coagulopathy with deficiency of …

Precision in transfusion medicine

MD Neal, BJ Hunt - JAMA, 2023 - jamanetwork.com
Blood transfusion management has come a long way since the introduction of blood banks
in the 1930s, leading to the widespread use of plasma and blood in the Second World War …

Impact of red blood cell transfusion and hemoglobin threshold on 1-year mortality among surgical sepsis survivors: a propensity score matching study

H Ma, S Li, R Dou, KY Lui, X Song, X Qian… - The American Journal of …, 2024 - Elsevier
Background Despite the fact that red blood cell (RBC) transfusion is commonly applied in
surgical intensive care unit (ICU), the effect of RBC transfusion on long-term outcomes …