Position-effect variegation (PEV) results when a gene normally in euchromatin is juxtaposed
with heterochromatin by rearrangement or transposition. When heterochromatin packaging …

Recent development of innovative tools for live imaging of actin filaments (F-actin) enabled
the detection of surprising nuclear structures responding to various stimuli, challenging …

Long-read, single-molecule real-time (SMRT) sequencing is routinely used to finish
microbial genomes, but available assembly methods have not scaled well to larger …

Fruit flies of the genus Drosophila have been an attractive and effective genetic model
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …

RNA-Seq is a powerful tool for the study of alternative splicing and other forms of alternative
isoform expression. Understanding the regulation of these processes requires sensitive and …

Drosophila melanogaster plays an important role in molecular, genetic, and genomic studies
of heredity, development, metabolism, behavior, and human disease. The initial reference …

Release 6, the latest reference genome assembly of the fruit fly Drosophila melanogaster,
was released by the Berkeley Drosophila Genome Project in 2014; it replaces their previous …

Salivary elicitors secreted by herbivorous insects can be perceived by host plants to trigger
plant immunity. However, how insects secrete other salivary components to subsequently …

To gain insight into how genomic information is translated into cellular and developmental
programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) …

Chromatin is composed of DNA and a variety of modified histones and non-histone proteins,
which have an impact on cell differentiation, gene regulation and other key cellular …