Bioluminescence imaging: progress and applications
CE Badr, BA Tannous - Trends in biotechnology, 2011 - cell.com
Application of bioluminescence imaging has increased tremendously in the past decade
and has significantly contributed to core conceptual advances in biomedical research. This …
and has significantly contributed to core conceptual advances in biomedical research. This …
Molecular imaging with reporter genes: has its promise been delivered?
I Serganova, RG Blasberg - Journal of Nuclear Medicine, 2019 - Soc Nuclear Med
The first reporter systems were developed in the early 1980s and were based on measuring
the activity of an enzyme—as a surrogate measure of promoter-driven transcriptional activity …
the activity of an enzyme—as a surrogate measure of promoter-driven transcriptional activity …
Detecting cancers through tumor-activatable minicircles that lead to a detectable blood biomarker
Earlier detection of cancers can dramatically improve the efficacy of available treatment
strategies. However, despite decades of effort on blood-based biomarker cancer detection …
strategies. However, despite decades of effort on blood-based biomarker cancer detection …
Targeting of hepatocellular carcinoma with glypican‐3‐targeting peptide ligand
Hepatocellular carcinoma is a common malignancy. The carcinoma cells express glypican‐
3 (GPC‐3) on the cell membrane. GPC‐3 is also expressed in melanoma cells. Therefore …
3 (GPC‐3) on the cell membrane. GPC‐3 is also expressed in melanoma cells. Therefore …
A survivin-driven, tumor-activatable minicircle system for prostate cancer theranostics
Gene vectors regulated by tumor-specific promoters to express transgenes specifically in
cancer cells are an emerging approach for cancer diagnosis and treatment. Minicircles are …
cancer cells are an emerging approach for cancer diagnosis and treatment. Minicircles are …
[HTML][HTML] Alpha-fetoprotein-targeted reporter gene expression imaging in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common cancers in Eastern Asia, and its
incidence is increasing globally. Numerous experimental models have been developed to …
incidence is increasing globally. Numerous experimental models have been developed to …
Drug discovery by molecular imaging and monitoring therapy response in lymphoma
S Kalimuthu, JH Jeong, JM Oh, BC Ahn - International journal of …, 2017 - mdpi.com
Molecular imaging allows a noninvasive assessment of biochemical and biological
processes in living subjects. Treatment strategies for malignant lymphoma depend on …
processes in living subjects. Treatment strategies for malignant lymphoma depend on …
Delivery approaches of gene therapy in hepatocellular carcinoma
F Duan, MGEH Lam - Anticancer research, 2013 - ar.iiarjournals.org
Gene therapy has the potential to provide therapeutic benefits to hepatocellular carcinoma
(HCC) patients and has been the subject of intense pre-clinical and clinical research in …
(HCC) patients and has been the subject of intense pre-clinical and clinical research in …
Requisites for successful theranostics with radionuclide-based reporter gene imaging
BC Ahn - Journal of Drug Targeting, 2014 - Taylor & Francis
Radionuclide-based theranostic strategy has been widely used in diagnosis and treatment
of patients with hyperthyroidism or differentiated thyroid cancer for a long time, and sodium …
of patients with hyperthyroidism or differentiated thyroid cancer for a long time, and sodium …
Intratumoral versus intravenous gene therapy using a transcriptionally targeted viral vector in an orthotopic hepatocellular carcinoma rat model
PURPOSE: To evaluate the feasibility of intratumoral delivery of adenoviral vector carrying a
bidirectional two-step transcriptional amplification (TSTA) system to amplify transcriptional …
bidirectional two-step transcriptional amplification (TSTA) system to amplify transcriptional …